Results 21 to 30 of about 3,165 (208)

Novel hypercapsulation RNA thermosensor variants in Neisseria meningitidis and their association with invasive meningococcal disease: a genetic and phenotypic investigation and molecular epidemiological study

open access: yesLancet Microbe, The, 2020
Summary: Background: Neisseria meningitidis is the causative agent of invasive meningococcal disease and the polysaccharide capsule is one of its major virulence factors.
Jens Karlsson   +2 more
exaly   +3 more sources

Temperature-dependent regulation of bacterial cell division hydrolases by the coordinated action of a regulatory RNA and the ClpXP protease [PDF]

open access: yesThe Cell Surface
A defining feature of bacteria is the peptidoglycan cell wall which provides structural integrity and prevents osmotic lysis. While peptidoglycan hydrolases are required for daughter cell separation, dysregulated cell wall degradation may result in cell ...
Viktor H. Mebus   +14 more
doaj   +2 more sources

Carbon quantum dots from silymarin extraction for multi-fluorescent sensors, photocatalysis, and anticancer activity applications [PDF]

open access: yesScientific Reports
In this work, water-soluble fluorescent carbon quantum dots were prepared by a one-stage hydrothermal method via a green synthesis route using silymarin extract from milk thistle seeds as a single precursor.
Salah Elkun   +3 more
doaj   +2 more sources

Engineering plant stress responses to combat climate change. [PDF]

open access: yesNew Phytol
New Phytologist, Volume 249, Issue 3, Page 1092-1094, February 2026.
Jones MA.
europepmc   +2 more sources

Development of a Temperature Senor Based on 19F-labeled Phosphorylated Ubiquitin

open access: yesChinese Journal of Magnetic Resonance, 2021
Ubiquitin (Ub) is a signaling protein in eukaryotic cells, and it functions in the processes of protein degradation and DNA repairing. The published data indicated that the phosphorylation of Ub on Ser65 leads to two stable solution conformations, which ...
Zhi-wu ZHANG   +5 more
doaj   +1 more source

OmpA, a Common Virulence Factor, Is Under RNA Thermometer Control in Yersinia pseudotuberculosis

open access: yesFrontiers in Microbiology, 2021
The outer membrane protein OmpA is a virulence factor in many mammalian pathogens. In previous global RNA structure probing studies, we found evidence for a temperature-modulated RNA structure in the 5'-untranslated region (5'-UTR) of the Yersinia ...
Daniel Scheller   +4 more
doaj   +1 more source

Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble

open access: yesNature Communications, 2021
Small heat shock proteins (sHsps) form large spherical assemblies and their regulation is not well understood. Here, the authors provide insights into the mechanism of Hsp26 activation by characterising phospho-mimetic mutants of yeast Hsp26.
Moritz Mühlhofer   +9 more
doaj   +1 more source

Phase Separation as a Molecular Thermosensor [PDF]

open access: yesDevelopmental Cell, 2020
How organisms sense temperature is a long-standing question. However, the identification of molecular thermosensors has been limited. Now, in a recent issue of Nature, Jung et al. demonstrate that phase separation of ELF3, a component of the circadian clock, acts as a thermosensor.
Changxuan, Li, Xiaofeng, Fang
openaire   +2 more sources

Recent Synthetic Biology Approaches for Temperature- and Light-Controlled Gene Expression in Bacterial Hosts

open access: yesMolecules, 2022
The expression of genes of interest (GOI) can be initiated by providing external stimuli such as temperature shifts and light irradiation. The application of thermal or light stimuli triggers structural changes in stimuli-sensitive biomolecules within ...
Jongdoo Choi   +3 more
doaj   +1 more source

A Prion-based Thermosensor in Plants [PDF]

open access: yesMolecular Cell, 2020
Some prion-like domains and low-complexity regions provide the multivalency required to facilitate protein phase separation to regulate protein function. Jung et al. (2020) demonstrate how natural selection of the ELF3 prion-like domain gives rise to an intuitive biological switch that directly responds to temperature.
Edward G, Wilkinson, Lucia C, Strader
openaire   +2 more sources

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