Results 321 to 330 of about 104,127 (354)

Convolution Neural Network-Based Prediction of Protein Thermostability

Journal of Chemical Information and Modeling, 2019
Most natural proteins exhibit poor thermostability, which limits their industrial application. Computer-aided rational design is an efficient purpose-oriented method that can improve protein thermostability.
Xing-Rong Fan, Jinsha Huang, Rui Zhang, Fei Wang, Qiuyu Zhang, Guanlin Li, Jinyong Yan, Houjin Zhang, Yunjun Yan, Li Xu   +9 more
semanticscholar   +1 more source

Thermostating in capillary electrophoresis

Chromatographia, 1997
The use of high voltages across a electrophoresis capillary will increase the temperature of the buffer due to Joule heating. As a result temperature control in CE is rather important since variations in the buffer temperature will result in changes in the pi-I of the buffer, peak shape, migration time, reproducibility, efficiency, 3-D structure of ...
Veraart, J.R., Gooijer, C., Lingeman, H.
openaire   +1 more source

Identification of a Hotspot Residue for Improving the Thermostability of a Flavin‐Dependent Monooxygenase

ChemBioChem, 2019
HadA is a flavin‐dependent monooxygenase that can catalyze the denitration and dehalogenation of a wide variety of toxicants such as pesticides. Although these enzymatic reactions are useful for bioremediation or biocatalysis, the application of HadA for
Pornkanok Pongpamorn, P. Watthaisong, P. Pimviriyakul, A. Jaruwat, Narin Lawan, P. Chitnumsub, P. Chaiyen   +6 more
semanticscholar   +1 more source

Thermotolerant and thermostable laccases

Biotechnology Letters, 2009
Laccases are phenol-oxidizing, usually four-copper containing metalloenzymes. For industrial and biotechnological purposes, laccases were among the first fungal oxidoreductases providing larger-scale applications such as removal of polyphenols in wine and beverages, conversion of toxic compounds and textile dyes in waste waters, and in bleaching and ...
Kristiina, Hildén, Terhi K, Hakala, Taina, Lundell   +2 more
openaire   +2 more sources

Protein engineering for thermostability

Trends in Biotechnology, 1990
Studies with small, monomeric proteins indicate that, to some extent, the effects of amino acid substitutions can be predicted. However, conformational and other changes may complicate the prediction. Site-directed mutagenesis is leading both to a better understanding of protein stability and to the production of more stable proteins.
Y, Nosoh, T, Sekiguchi
openaire   +2 more sources

Thermostability of cytomegalovirus strains

Archiv für die gesamte Virusforschung, 1968
Cytomegalovirus (CMV) has been considered a difficult virus to isolate and study because of its apparent lability. Investigations of the thermostability of strains have yielded discrepant results, some of which appear to be due to the diluents used. The stability of three CMV strains at 37°, 25° and 3°C has been studied here.
B B, Wentworth, P W, Gloyd
openaire   +2 more sources

Thermostable Proteins

2016
Delineation of the Conformational Thermostability of Hyperthermophilic Proteins Based on Structural and Biophysical Analyses Atsushi Mukaiyama and Kazufumi Takano Role of Packing, Hydration, and Fluctuations on Thermostability Fabio Sterpone and Simone Melchionna Analyzing Protein Rigidity for Understanding and Improving Thermal Adaptation Doris L ...
openaire   +1 more source

Thermostability engineering of industrial enzymes through structure modification

Applied Microbiology and Biotechnology, 2022
Nima Ghahremani Nezhad, R. Rahman, Yahaya M. Normi, Siti Nurbaya Oslan, Fairolniza Mohd. Shariff, T. Leow   +5 more
semanticscholar   +1 more source

Transfer of nongenetic thermostability from genetically thermostable to genetically thermolabile poliovirus

Archiv f�r die gesamte Virusforschung, 1961
Adding the genetically thermostablecr i mutant of the Akron strain of type 1 poliovirus to the genetically thermolabile Akronca 30 mutant before infection of monkey kidney tissue culture sheets resulted in an average 17-fold increase in the heat-surviving fraction of theca 30 virus progeny. Mixing the 2 viruses after
G R, DUBES, O, TOLBERT
openaire   +2 more sources

Enhancing the Thermostability of Highly Active and Glucose-Tolerant β-Glucosidase Ks5A7 by Directed Evolution for Good Performance of Three Properties.

Journal of Agricultural and Food Chemistry, 2018
A high-performance β-glucosidase for efficient cellulose hydrolysis needs to excel in thermostability, catalytic efficiency, and resistance to glucose inhibition.
Lichuang Cao, Shuifeng Li, Xin Huang, Zongmin Qin, Wei Kong, W. Xie, Yuhuan Liu   +6 more
semanticscholar   +1 more source