Variants of a Thermus aquaticus DNA polymerase with increased selectivity for applications in allele- and methylation-specific amplification. [PDF]
PLoS ONE, 2014 The selectivity of DNA polymerases is crucial for many applications. For example, high discrimination between the extension of matched versus mismatched primer termini is desired for the detection of a single nucleotide variation at a particular locus ...
Matthias Drum +4 more
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Growth models of Thermus aquaticus and Thermus scotoductus [PDF]
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012 Members of the genus Thermus family are signifiant producers of secondary metabolites, which are very commonly used in industry. Beside the productivity, it is also important to study the growth curve of each strain.
Libor Babák +2 more
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Complete Genome Sequence of Thermus aquaticus Y51MC23. [PDF]
PLoS ONE, 2015 Thermus aquaticus Y51MC23 was isolated from a boiling spring in the Lower Geyser Basin of Yellowstone National Park. Remarkably, this T. aquaticus strain is able to grow anaerobically and produces multiple morphological forms. Y51MC23 is a Gram-negative,
Phillip J Brumm +7 more
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Crystal structure of a Thermus aquaticus diversity-generating retroelement variable protein. [PDF]
PLoS ONE, 2019 Diversity-generating retroelements (DGRs) are widely distributed in bacteria, archaea, and microbial viruses, and bring about unparalleled levels of sequence variation in target proteins.
Sumit Handa +2 more
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A robust strategy for overexpression of DNA polymerase from Thermus aquaticus using an IPTG-independent autoinduction system in a benchtop bioreactor [PDF]
Scientific ReportsThe DNA polymerase derived from Thermus aquaticus is the most widely utilized among various DNA polymerases, indicating its significant economic importance. Consequently, efforts to achieve a substantial yield of Taq DNA polymerase (Taq-pol) are ongoing.
Fina Amreta Laksmi +11 more
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Inhibitory Effect of Bridged Nucleosides on Thermus aquaticus DNA Polymerase and Insight into the Binding Interactions. [PDF]
PLoS ONE, 2016 Modified nucleosides have the potential to inhibit DNA polymerases for the treatment of viral infections and cancer. With the hope of developing potent drug candidates by the modification of the 2',4'-position of the ribose with the inclusion of a bridge,
Sung-Kun Kim +5 more
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A Novel Exopolysaccharide from the Biofilm of Thermus aquaticus YT-1 Induces the Immune Response through Toll-like Receptor 2 [PDF]
Journal of Biological Chemistry, 2011 Miao-Hsia Lin, Yu-Liang Yang, Fuu Sheu
exaly +4 more sources
Live culture-based qPCR screening of Taq DNA polymerase variants for resistance to PCR inhibitors [PDF]
Frontiers in Bioengineering and BiotechnologyWe present a live culture PCR (LC-PCR) workflow that enables direct screening of randomly mutagenized Thermus aquaticus (Taq) and Klentaq1 DNA polymerase libraries without enzyme purification.
Milko B. Kermekchiev +3 more
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Conformational dynamics of Thermus aquaticus DNA polymerase I during catalysis. [PDF]
J Mol Biol, 2014 Xu C, Maxwell BA, Suo Z.
europepmc +3 more sources
High-yield cycloamylose production from sweet potato starch using Pseudomonas isoamylase and Thermus aquaticus 4-α-glucanotransferase. [PDF]
Food Sci Biotechnol, 2016 Chu S +6 more
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