Results 261 to 270 of about 89,035 (286)

Structure‐based discovery of thiamine uptake inhibitors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel   +2 more
wiley   +1 more source

Production of the Antimicrobial Roseoflavin With Genetically Engineered Corynebacterium glutamicum. [PDF]

open access: yesMicrob Biotechnol
Brito LF   +4 more
europepmc   +1 more source

The miR172a‐ERF416/413 module regulates soybean seed traits

open access: yesJournal of Integrative Plant Biology, Volume 67, Issue 11, Page 2999-3013, November 2025.
The microRNA miR172a cleaves transcripts of the transcription factor genes ERF416 and ERF413. ERF416 and ERF413 affect seed size/weight by regulating genes encoding a regulator of cell proliferation and a sugar transporter. ERF416 haplotypes correlate with seed weight and total seed lipids, providing information for breeding high‐oil high‐yield soybean
Meng Jin   +24 more
wiley   +1 more source

The Energetic Collapse of the Alzheimer's Brain: Metabolic Inflexibility Across Cells and Networks

open access: yesJournal of Neurochemistry, Volume 169, Issue 11, November 2025.
Metabolic inflexibility in Alzheimer's disease. Schematic illustrating the biphasic trajectory of metabolic activity relative to canonical Alzheimer's disease (AD) biomarkers. In the presymptomatic phase (~15–20 years before cognitive symptoms), amyloid accumulation is accompanied by glial‐driven hypermetabolism, reflecting early metabolic ...
Nicholas J. Constantino   +2 more
wiley   +1 more source

Exploring neuropsychiatric manifestations of vitamin B complex deficiencies. [PDF]

open access: yesFront Psychiatry
Han A   +6 more
europepmc   +1 more source

Impact of Street Food Availability on Nutritional Intake and Diet‐Related Health Outcomes: A Systematic Review

open access: yesObesity Reviews, Volume 26, Issue 11, November 2025.
ABSTRACT The community food environment influences access to food, which depends on the type of food venues available. However, studies predominantly focus on the Global North, often neglecting culturally relevant food sources in the Global South, like street food (SF) stalls. SF are a popular, affordable, and convenient source of energy and nutrients,
Jose‐Benito Rosales Chavez   +2 more
wiley   +1 more source

Thiamine Deficiency and Neuroinflammation Are Important Contributors to Alcohol Use Disorder. [PDF]

open access: yesPathophysiology
Kalapatapu N   +5 more
europepmc   +1 more source

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