Results 111 to 120 of about 19,767 (240)

Thiamine Deficiency Leading to Refractory Lactic Acidosis in a Pediatric Patient

Case Reports in Critical Care, 2017
Thiamine plays a critical role in energy metabolism. Critically ill children and adults may develop thiamine deficiency with ultimately increased mortality due to potentially irreversible consequences of severe type B lactic acidosis. We report a case of
Alicia M. Teagarden, Brian D. Leland, Courtney M. Rowan, Riad Lutfi   +3 more
doaj   +1 more source

Pathogenic Variants in the PRKRA Gene Can Result in a Rapid‐Onset Dystonia‐Parkinsonism‐like Phenotype

Movement Disorders, EarlyView.
Maeve Bradley, Senan Maher, Christian Espinoza‐Vinces, Kathleen Gorman, Tim Lynch, Richard A. Walsh, Alberto J. Espay, Conor Fearon   +7 more
wiley   +1 more source

Clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, EarlyView.
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara, Minna Kraatari‐Tiri, Jussi‐Pekka Tolonen, Marko Merikukka, IDGEN Study Group, Hannaleena Kokkonen, Teija Paakkola, Susanna Varis, Antti Dahl, Jarmo Körkkö, Jonna Komulainen‐Ebrahim, Jukka Moilanen, Johanna Uusimaa, Outi Kuismin, Elisa Rahikkala   +14 more
wiley   +1 more source

The Implications of Atlantic Salmon (Salmo salar L.) Fatty Acid Profiles for Their Thiamine Status

Ecology and Evolution
Thiamine deficiency is an ongoing issue across the Northern Hemisphere, causing reproductive failure in multiple salmonid populations. In the Baltic Sea, a large brackish water system in northern Europe, previous research has suggested that this ...
Vittoria Todisco, Marc M. Hauber, Michael T. Brett, Charlotte Axén, Kjetil Hindar, Petter Tibblin, Samuel Hylander   +6 more
doaj   +1 more source

High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children.

PLoS Neglected Tropical Diseases, 2017
BackgroundThiamine deficiency is thought to be an issue in Cambodia and throughout Southeast Asia due to frequent clinical reports of infantile beriberi.
Kyly C Whitfield, Geoffry Smith, Chhoun Chamnan, Crystal D Karakochuk, Prak Sophonneary, Khov Kuong, Marjoleine Amma Dijkhuizen, Rathavuth Hong, Jacques Berger, Tim J Green, Frank Tammo Wieringa   +10 more
doaj   +1 more source

Air embolism secondary to suspected lymphatic tissue disruption with severe exercise‐induced pulmonary haemorrhage

Equine Veterinary Education, EarlyView.
Summary Air embolism is rare in horses and typically associated with complications following intravenous catheterisation or other medical procedures. Exercise‐induced pulmonary haemorrhage (EIPH) is common in racehorses but not usually associated with air embolism. This report describes a case of air embolism in a 4‐year‐old Thoroughbred with EIPH. The
J. Wittenberg, K. Drozdzewska, K. Landmann, A. Voß, K. Kunze, D. Rutenberg, A. D. Gruber, H. Gehlen   +7 more
wiley   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Thiamine Concentration in Human Milk Is Correlated With Maternal and Infant Thiamine Status: A Cross‐Sectional Analysis of the Lao Thiamine Study

Maternal and Child Nutrition
The human milk content of some micronutrients including thiamine depends on maternal status, and if low, breastfed infants are at risk of deficiency. Thiamine deficiency remains an important cause of morbidity and mortality among infants in Asia.
Sonja Y. Hess, Charles D. Arnold, Taryn J. Smith, Lindsay H. Allen, Daniela Hampel, Kerry S. Jones, Damon A. Parkington, Sarah R. Meadows, Dalaphone Sitthideth, Sengchanh Kounnavong   +9 more
doaj   +1 more source

Beriberi Induced Cardiomyopathy Requiring Salvage Venoarterial Extracorporeal Membrane Oxygenation

Case Reports in Critical Care, 2016
Beriberi refers to a constellation of symptoms caused primarily by thiamine (vitamin B1) deficiency. An acute and fulminant presentation of this rare condition has been described in the literature as “Shoshin” beriberi which is characterized by ...
Aditya Shah, Samir Patel, Sorabh Kothari, Jennifer Denk   +3 more
doaj   +1 more source

Gut microbial features can predict host phenotype response to protein deficiency. [PDF]

, 2018
Malnutrition remains a major health problem in low- and middle-income countries. During low protein intake, <0.67 g/kg/day, there is a loss of nitrogen (N2 ) balance, due to the unavailability of amino acid for metabolism and unbalanced protein ...
Dugas, Lara R, Forrester, Terrence, Gilbert, Jack A, Layden, Brian T, Navarro, Guadalupe, Sharma, Anukriti   +5 more
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