Results 111 to 120 of about 449,811 (276)
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu +7 more
wiley +1 more source
Clinical and genetic characterization of intellectual disability
Developmental Medicine &Child Neurology, EarlyView.This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara +14 more
wiley +1 more source
Altered sensorium in a patient with chronic kidney disease: Unmasking the unusual
Journal of Current Research in Scientific MedicineWernicke encephalopathy (WE) is an acute neuropsychiatric syndrome caused by thiamine deficiency, classically associated with chronic alcohol abuse. However, it is increasingly recognized in nonalcoholic settings.
Saif Quaiser, Ruhi Khan
doaj +1 more source
S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
The FEBS Journal, EarlyView.S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Thiamine Deficiency Is Common Among Emergency Department Oncology Patients
, 2018 Background: Thiamine deficiency is associated with significant morbidity that may be precipitated by acute illness. Due to metabolic demands of cancer and difficulty maintaining adequate nutrition, oncology patients may be at higher risk of thiamine ...
France, J +7 more
core +1 more source
Clinical Ophthalmology, 2014 Sean M Gratton, Byron L LamBascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, USAAbstract: Visual loss due to optic neuropathy is a rare manifestation of thiamine deficiency.
Gratton SM, Lam BL
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Effect of thiamine deficiency on canine gastric secretion of acid
, 1959 A study was undertaken to determine the effect of thiamine deficiency on the hydrochloric acid output of vagally denervated gastric pouches (Heidenhain-type) and vagally innervated gastric pouches (Pavlov-type) in dogs.
Marjorie K. Lavers +2 more
core +1 more source
Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance
The FEBS Journal, EarlyView.Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
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Thiamine (Vitamin B1) Deficiency (Presentation)
, 2023 Overview of thiamine deficiency and its neuro-ophthalmic manifestations with an illustrative case example and discussion of clinical presentation, relevant biochemistry, testing, risk factors, and treatment.
Nirupama Devanathan; Devin D. Mackay, MD
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