Results 91 to 100 of about 19,401 (288)

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Postpartum thiamine deficiency in a Karen displaced population.

, 2001
BACKGROUND: Before its recognition, infantile beriberi was the leading cause of infant death in camps for displaced persons of the Karen ethnic minority on Thailand's western border.
Rose McGready, Simpson, JA, Munger, RG, Lilly Dubowitz, Böhm, V, Ron G Munger, Changbumrung, S, Thein Cho, Nicholas J White, Dubowitz, L, Sauberlich, HE, Mcgready, Rose, Julie A Simpson, Cho, T, Supranee Changbumrung, White, NJ, White, Nicholas, Nosten, F, Howerde E Sauberlich, Volker Böhm, François Nosten, Mcgready, R   +21 more
core   +1 more source

Pro‐197 mutations confer resistance to thiencarbazone but not to foramsulfuron in ALS‐resistant Poa annua populations

Pest Management Science, EarlyView.
Foramsulfuron remains effective on Pro‐197 Poa annua, but co‐formulation with thiencarbazone reduces efficacy due to limited activity and antagonism. Therefore, foramsulfuron + thiencarbazone should be used in fields without ALS‐resistant weeds to ensure effective in‐crop control.
Vijaya Bhaskar Alwarnaidu Vijayarajan, Iniya Vijayakumar, Rafa Ruiz‐Partida, Fabian Runge, Joel Torra, Jorge Lozano‐Juste, Patrick Dermot Forristal   +6 more
wiley   +1 more source

Wernicke encephalopathy in pregnancy associated with hyperemesis gravidarum: a case report

BMC Pregnancy and Childbirth
Background Wernicke Encephalopathy is a rare neurological disorder caused by thiamine deficiency, which can occur in pregnant women with severe hyperemesis gravidarum.
Anna Weronika Szablewska, Agnieszka Czerwińska-Osipiak, Aleksandra Krawczyk, Radosław Piekarski   +3 more
doaj   +1 more source

Free-thiamine is a potential biomarker of thiamine transporter-2 deficiency: a treatable cause of Leigh syndrome

, 2016
Thiamine transporter-2 deficiency is caused by mutations in the SLC19A3 gene. As opposed to other causes of Leigh syndrome, early administration of thiamine and biotin has a dramatic and immediate clinical effect.
Gort, Laura, Ortigoza-Escobar, Juan Darío, Darin, Niklas,, Casado, Mercedes, Artuch, Rafael, Hernández, María, Garcia-Villoria, Judit, Mayr, Johannes A, Rodríguez-Pombo, Pilar, Oyarzabal, Alfonso, Molero-Luis, Marta, Pérez-Dueñas, Belén, Tondo, Mireia, Ribes, Antonia, Garcia-Cazorla, Angels, Arias, Angela, Serrano, Mercedes   +16 more
core   +1 more source

Epidemiological distribution of MRI‐based presumptive imaging diagnoses in a large general population of cats with suspected epileptic seizures

Veterinary Record, EarlyView.
Abstract Background The reported prevalence of feline idiopathic epilepsy (IE) and presumptive imaging diagnoses based on magnetic resonance imaging (MRI) varies depending on factors such as differences between primary care versus referral study populations.
Anna Knebel, Sebastian Meller, Julien Labruyère, Holger A. Volk   +3 more
wiley   +1 more source

Thiamine Deficiency in Infancy

, 2014
Investigators at Tel Aviv University, Loewenstein Rehabilitation Hospital, Schneider Children's Medical Center, and other centers in Israel report the clinical presentation of acute encephalopathy in 11 children and the long-term sequelae of 8 who ...
John J Millichap, J Gordon Millichap
core   +1 more source

Genetic Tools in the Nakaseomyces clade for Evolutionary Comparisons of Signal Transduction Pathways

Yeast, EarlyView.
ABSTRACT The genus Nakaseomyces provides four species that are closely related but have different characteristics. For example, N. glabratus (formerly known as Candida glabrata) is a common human pathogen, whereas N. bracarensis and N. nivariensis have been isolated in clinical settings but are not common human pathogens. N.
Maria Abraham, Christine L. Iosue, Dennis D. Wykoff   +2 more
wiley   +1 more source

Thiamin deficiency and brain disorders [PDF]

Nutrition Research Reviews, 2003
AbstractThiamin plays a key role in the maintenance of brain function. Thiamin diphosphate is cofactor for several enzymes involved in glucose metabolism whereas thiamin triphosphate has distinct properties at the neuronal membrane. Thiamin metabolism in the brain is compartmented between neurons and neighbouring glial cells.
openaire   +2 more sources

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source