Is transketolase-like protein, TKTL1, transketolase?
Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2013 Until recently it was assumed that the transketolase-like protein (TKTL1) detected in the tumor tissue, is catalytically active mutant form of human transketolase (hTKT). Human TKT shares 61% sequence identity with TKTL1. And the two proteins are 77% homologous at the amino acid level.
Olga N Solovjeva, German A Kochetov
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Structure-Based Discovery and Synthesis of Potential Transketolase Inhibitors
Molecules, 2018 Transketolase (TKL) plays a key role in plant photosynthesis and has been predicted to be a potent herbicide target. Homology modeling and molecular dynamics simulation were used to construct a target protein model.
Zhijin Fan, , Bin Zhao
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Transketolase Is Identified as a Target of Herbicidal Substance α-Terthienyl by Proteomics
Toxins, 2018 α-terthienyl is a natural phytotoxin isolated originally from Flaveria bidentis (L.) Kuntze. The bioassay presented here shows the strong herbicidal activity of α-terthienyl on Digitaria sanguinalis, Arabidopsis thaliana and Chlamydomonas reinhardtii ...
, Bin Zhao, Jingao Dong
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The Prevalence of Thiamine Deficiency and Associated Factors among Adult Population in Shiraz, Southern Iran [PDF]
International Journal of Nutrition Sciences, 2020 Background: Thiamine is an essential nutrient, and its deficiency is accompanied by nervous and cardiovascular disorders. This study aimed to assess the prevalence of thiamine deficiency and associated factors among adults in Shiraz, southern Iran ...
Zahra Hassanzadeh-Rostami +5 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundNoninvasive evaluation of the expression of angiopoietin-2 (Ang-2) and transketolase (TKT) in hepatocellular carcinoma (HCC) is of great significance for the clinical development of individualized treatment plans.
Jing Zheng +11 more
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Revealing the functions of the transketolase enzyme isoforms in Rhodopseudomonas palustris using a systems biology approach. [PDF]
PLoS ONE, 2011 BACKGROUND: Rhodopseudomonas palustris (R. palustris) is a purple non-sulfur anoxygenic phototrophic bacterium that belongs to the class of proteobacteria. It is capable of absorbing atmospheric carbon dioxide and converting it to biomass via the process
Chia-Wei Hu +6 more
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Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase [PDF]
Open Biology, 2015 The network of protein–protein interactions of the Dictyostelium discoideum autophagy pathway was investigated by yeast two-hybrid screening of the conserved autophagic proteins Atg1 and Atg8.
Ana Mesquita +5 more
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Carbohydrate Metabolism Parameters of Adult Glial Neoplasms According to Immunohistochemical Profile
Biomedicines, 2022 This research aimed to investigate the interrelationship of carbohydrate metabolism parameters and immunohistochemical characteristics of glial tumors. Tumor tissue, peritumoral area, and adjacent noncancerous tissue fragments of 20 patients with gliomas
Larisa Obukhova +7 more
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A δ38 deletion variant of human transketolase as a model of transketolase-like protein 1 exhibits no enzymatic activity. [PDF]
PLoS ONE, 2012 Besides transketolase (TKT), a thiamin-dependent enzyme of the pentose phosphate pathway, the human genome encodes for two closely related transketolase-like proteins, which share a high sequence identity with TKT.
Stefan Schneider +5 more
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Frontiers in Microbiology, 2022 Background: Erythritol is a zero-calorie sweetener that is widely used in the food, pharmaceutical, and medical industries. Crude glycerol is the main by-product of biodiesel, and the effective utilization of crude glycerol will help to improve biodiesel
Shuling Yang +6 more
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