Results 41 to 50 of about 8,654 (179)

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 795-806, August 2026.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

Kinetic parameter prediction using neural networks identifies limitations to C4 photosynthesis

New Phytologist, Volume 251, Issue 3, Page 1578-1594, August 2026.
Schematic overview of the generation of artificial training data and training of neural networks in C4TUNE. Summary Kinetic models of photosynthesis enable time‐resolved predictions of traits related to this key process and provide the means to identify factors limiting photosynthesis.
Philipp Wendering, John Ferguson, Rudan Xu, Johannes Kromdijk, Zoran Nikoloski   +4 more
wiley   +1 more source

Extracellular Vesicles From Human Fallopian Tubes Enhance IVF Embryo Development and Contain Functional Proteins Including YWHAZ

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs) in the mammalian oviduct constitute a key maternal regulatory system that maintains redox balance during early embryogenesis, yet their molecular cargo and functional relevance in human embryos remain poorly defined.
Yuehan Li, Wenjing Xiong, Limin Gao, Mingwei Lv, Fei Li, Rui Long, Chang Liu, Jianbo Wei, Meng Wang, Chenlu Zhang, Qiuyu Yu, Na Guo, Lei Jin, Cong Sui   +13 more
wiley   +1 more source

Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy

Diabetes & Vascular Disease Research, 2020
Thiamine prevents high glucose-induced damage in microvasculature, and progression of retinopathy and nephropathy in diabetic animals. Impaired thiamine availability causes renal damage in diabetic patients. Two single-nucleotide polymorphisms in SLC19A3
Elena Beltramo, Aurora Mazzeo, Tatiana Lopatina, Marina Trento, Massimo Porta   +4 more
doaj   +1 more source

Co‐Production of Mycoprotein, Carotenoids, and B Vitamins From Cheese Whey by Neurospora intermedia

Journal of Food Science, Volume 91, Issue 7, July 2026.
ABSTRACT Cheese whey, a nutrient‐rich dairy byproduct that requires management due to its high organic load, was valorized using an integrated biorefinery platform with the edible fungus Neurospora intermedia to simultaneously produce mycoprotein, carotenoids, and B vitamins (B1, B2, B3, B6).
Farzaneh Dianatdar, Zahra Etemadifar, Mohammad J. Taherzadeh   +2 more
wiley   +1 more source

Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from l-arabinose

Data in Brief, 2018
The dataset presented in this article is related to the research article entitled “One-pot, two-step transaminase and transketolase synthesis of l-gluco-heptulose from l-arabinose” (Bawn et al., 2018 in press) [1].
Maria Bawn, Fabiana Subrizi, Gary J. Lye, Tom D. Sheppard, Helen C. Hailes, John M. Ward   +5 more
doaj   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang, Junduo Zhao, Xu'an Huang, Weiyun Chen, Jianxiong Shen   +4 more
wiley   +1 more source

Peroxisomes and peroxisomal transketolase and transaldolase enzymes are essential for xylose alcoholic fermentation by the methylotrophic thermotolerant yeast, Ogataea (Hansenula) polymorpha

Biotechnology for Biofuels, 2018
Background Ogataea (Hansenula) polymorpha is one of the most thermotolerant xylose-fermenting yeast species reported to date. Several metabolic engineering approaches have been successfully demonstrated to improve high-temperature alcoholic fermentation ...
Olena O. Kurylenko, Justyna Ruchala, Roksolana V. Vasylyshyn, Oleh V. Stasyk, Olena V. Dmytruk, Kostyantyn V. Dmytruk, Andriy A. Sibirny   +6 more
doaj   +1 more source

From the Proteome to Therapeutics: A Multi‐Database Approach to Drug Discovery in Periodontitis—An Exploratory Pilot Study

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 990-1004, July 2026.
ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo, Annette Murr, Birte Holtfreter, Sebastian‐Edgar Baumeister, Peter Meisel, Uwe Völker, Werner Weitschies, Henry Völzke, Philipp Kanzow, Elke Hammer, Manuela Gesell Salazar, Thomas Kocher   +11 more
wiley   +1 more source

Overexpression of Transketolase Relieves xylA Repression and Enhances Xylose Utilization in Saccharomyces cerevisiae During Mixed Sugar Fermentation

GCB Bioenergy
Metabolic engineering of Saccharomyces cerevisiae has enabled xylose‐fermenting yeast strains. However, the bioavailability dilemma of xylose has become the core bottleneck restricting the economy of lignocellulose.
Si Xu, Wanli Cheng, Huanan Li, Jiashu Liu, Kexin Chen, Zhengbing Jiang   +5 more
doaj   +1 more source