Results 31 to 40 of about 8,762 (179)
Frontiers in ImmunologyObjectiveTo explore the role of transketolase (TKT) in the immunotherapy and prognosis of hepatocellular carcinoma (HCC).Materials and methodsTKT expression across various cancers and its associations with tumor immunity and prognosis were analyzed using
Xuan-Yu Gu +6 more
doaj +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2019 The review article presents an analysis of the literature on the effect of thiamine and its derivatives on the metabolism in cells and its role in the pathogenesis of complications of diabetes mellitus.
K. Singh, T. Yuzvenko, D. Kogut
doaj +1 more source
Exploring the Potential of Flunarizine for Cisplatin-Induced Painful Uremic Neuropathy in Rats [PDF]
International Neurourology Journal, 2011 Purpose The present study was designed to explore the potential of flunarizine for cisplatin induced painful uremic neuropathy in rats. Methods Cisplatin (2 mg/kg; i.p., for 5 consecutive days) was administered and renal uremic markers i.e., serum ...
Arunachalam Muthuraman +2 more
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Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling
Biotechnology and Bioengineering, EarlyView.ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana +4 more
wiley +1 more source
VIEW, EarlyView.(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao +8 more
wiley +1 more source
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation
Cell Death and Disease, 2022 Transketolase (TKT) which is an important metabolic enzyme in the pentose phosphate pathway (PPP) participates in maintaining ribose 5-phosphate levels. TKT is necessary for maintaining cell growth.
Minle Li +10 more
doaj +1 more source
The FEBS Journal, EarlyView.Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra +4 more
wiley +1 more source
Photosynthetic Responses to Rising CO2 and Temperature: Mechanisms, Models, and Field Evidence
Global Change Biology, Volume 32, Issue 9, September 2026.This review revisits the mechanistic basis of CO2 × temperature interactions in C3 photosynthesis and evaluates how subsequent research has refined this framework. We synthesize evidence showing how acclimation, diffusive limitations, and canopy processes modify photosynthetic responses to rising CO2 and warming across scales.
Carl J. Bernacchi, Amanda P. Cavanagh
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis +2 more
wiley +2 more sources
Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 468-484, September 2026.ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri +13 more
wiley +1 more source