Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]
, 2019 Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Adams +154 more
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Mìžnarodnij Endokrinologìčnij Žurnal, 2019 The review article presents an analysis of the literature on the effect of thiamine and its derivatives on the metabolism in cells and its role in the pathogenesis of complications of diabetes mellitus.
K. Singh, T. Yuzvenko, D. Kogut
doaj +1 more source
Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells. [PDF]
, 2015 A network model for the determination of tumor metabolic fluxes from (13)C NMR kinetic isotopomer data has been developed and validated with perfused human DB-1 melanoma cells carrying the BRAF V600E mutation, which promotes oxidative metabolism.
Blair, Ian A +9 more
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Leaf apoplastic proteome composition in UV-B treated Arabidopsis thaliana mutants impaired in extracellular glutathione degradation [PDF]
, 2016 In plants, environmental perturbations often result in oxidative reactions in the apoplastic space, which are counteracted for by enzymatic and non-enzymatic antioxidative systems, including ascorbate and glutathione. The occurrence of the latter and its
Arrigoni, Giorgio +2 more
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Diphenyl urea derivatives as inhibitors of transketolase: a structure-based virtual screening. [PDF]
PLoS ONE, 2012 Transketolase is an enzyme involved in a critical step of the non-oxidative branch of the pentose phosphate pathway whose inhibition could lead to new anticancer drugs. Here, we report new human transketolase inhibitors, based on the phenyl urea scaffold,
Cristian Obiol-Pardo +3 more
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Transketolase Is Identified as a Target of Herbicidal Substance α-Terthienyl by Proteomics
Toxins, 2018 α-terthienyl is a natural phytotoxin isolated originally from Flaveria bidentis (L.) Kuntze. The bioassay presented here shows the strong herbicidal activity of α-terthienyl on Digitaria sanguinalis, Arabidopsis thaliana and Chlamydomonas reinhardtii ...
Bin Zhao +4 more
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Novel strategies to improve co-fermentation of pentoses with D-glucose by recombinant yeast strains in lignocellulosic hydrolysates [PDF]
, 2012 Economically feasible production of second-generation biofuels requires efficient co-fermentation of pentose and hexose sugars in lignocellulosic hydrolysates under very harsh conditions. Baker’s yeast is an excellent, traditionally used ethanol producer
Boles, Eckhard +3 more
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Microbiology Spectrum, 2023 Despite advances in rapid molecular techniques for tuberculosis (TB) diagnostics, there is an unmet need for a point-of-care, nonsputum-based test. Previously, through a T7 phage antigen display platform and immunoscreening, we identified that the serum ...
Jaya Talreja +4 more
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Seizure Disorders in Goats and Sheep. [PDF]
, 2016 BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
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Heterologous expression of human transketolase [PDF]
The International Journal of Biochemistry & Cell Biology, 1998 Transketolase belongs to the family of thiamin diphosphate dependent enzymes. The aim of this study was to establish a bacterial expression system for human transketolase in order to investigate the functional characteristics of mammalian transketolases. The level of recombinant human enzyme expressed in Escherichia coli was modest.
Schenk, Gerhard +2 more
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