Results 21 to 30 of about 16,581 (212)

Overexpression of transketolase-like gene 1 is associated with cell proliferation in uterine cervix cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2009
Background Tumor cells need large energy and nucleic acids to proliferate and grow. For most of their energy needs, cancer cells depend more on glycolysis. For most of their nucleic acids needs, cancer cells depend more on the nonoxidative pathway of the
Chen Hui   +5 more
doaj   +1 more source

Overexpression of Plastid Transketolase in Tobacco Results in a Thiamine Auxotrophic Phenotype [PDF]

open access: yes, 2015
To investigate the effect of increased plastid transketolase on photosynthetic capacity and growth, tobacco (Nicotiana tabacum) plants with increased levels of transketolase protein were produced.
Fisk, S   +7 more
core   +2 more sources

Seeing double: the low-carb diet [PDF]

open access: yes, 2013
No abstract ...
Drummond, Russell S.   +4 more
core   +1 more source

A ‘Split-Gene’ Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans: Structure and Biochemical Characterization

open access: yesFrontiers in Microbiology, 2020
A novel transketolase has been reconstituted from two separate polypeptide chains encoded by a ‘split-gene’ identified in the genome of the hyperthermophilic bacterium, Carboxydothermus hydrogenoformans.
Paul James   +5 more
doaj   +1 more source

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme [PDF]

open access: yesOpen Biology, 2012
The transketolase (TKT) enzyme in Mycobacterium tuberculosis represents a novel drug target for tuberculosis treatment and has low homology with the orthologous human enzyme.
Elizabeth Fullam   +4 more
doaj   +1 more source

Reduced Thiamine Availability and Hyperglycemia Impair Thiamine Transport in Renal Glomerular Cells through Modulation of Thiamine Transporter 2

open access: yesBiomedicines, 2021
Thiamine helps transketolase in removing toxic metabolites, counteracting high glucose-induced damage in microvascular cells, and progression of diabetic retinopathy/nephropathy in diabetic animals.
Aurora Mazzeo   +6 more
doaj   +1 more source

Simplified immobilisation method for histidine-tagged enzymes in poly(methyl methacrylate) microfluidic devices [PDF]

open access: yes, 2017
Article in press. Kulsharova, G., New BIOTECHNOLOGY (2017), https://doi.org/10.1016/j.nbt.2017.12.004Poly(methyl methacrylate) (PMMA) microfluidic devices have become promising platforms for a wide range of applications.
Baganz, Frank   +4 more
core   +3 more sources

Acidosis Activates the Nrf2 Pathway in Renal Proximal Tubule-Derived Cells through a Crosstalk with Renal Fibroblasts

open access: yesAntioxidants, 2023
Crosstalk of renal epithelial cells with interstitial fibroblasts plays an important role in kidney pathophysiology. A previous study showed that crosstalk between renal epithelial cells and renal fibroblasts protects against acidosis-induced damage.
Marie-Christin Schulz   +5 more
doaj   +1 more source

Cloning, expression and characterization of sugarcane (Saccharum officinarum L.) transketolase [PDF]

open access: yes, 2013
Pentose phosphate pathway (PPP) composed of two functionally-connected phases, the oxidative and non-oxidative phase. Both phases catalysed by a series of enzymes.
Go, Rusea   +2 more
core   +1 more source

Structure-Based Discovery and Synthesis of Potential Transketolase Inhibitors

open access: yesMolecules, 2018
Transketolase (TKL) plays a key role in plant photosynthesis and has been predicted to be a potent herbicide target. Homology modeling and molecular dynamics simulation were used to construct a target protein model.
Jingqian Huo   +6 more
doaj   +1 more source

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