Results 1 to 10 of about 201,980 (166)

Glutathione S-Transferases in Cancer

open access: yesAntioxidants, 2021
In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities.
Rahul Raj Singh, Katie M. Reindl
doaj   +2 more sources

Plant Glutathione Transferases and Light

open access: yesFrontiers in Plant Science, 2019
The activity and expression of glutathione transferases (GSTs) depend on several less-known endogenous and well-described exogenous factors, such as the developmental stage, presence, and intensity of different stressors, as well as on the absence or ...
Ágnes Gallé   +6 more
doaj   +2 more sources

The Multifaceted Role of Glutathione S-Transferases in Health and Disease

open access: yesBiomolecules, 2023
In humans, the cytosolic glutathione S-transferase (GST) family of proteins is encoded by 16 genes presented in seven different classes. GSTs exhibit remarkable structural similarity with some overlapping functionalities. As a primary function, GSTs play
Aslam M. A. Mazari   +5 more
semanticscholar   +1 more source

Functional and Structural Diversity of Insect Glutathione S-transferases in Xenobiotic Adaptation

open access: yesInternational Journal on Biological Sciences, 2022
As a superfamily of multifunctional enzymes that is mainly associated with xenobiotic adaptation, glutathione S-transferases (GSTs) facilitate insects' survival under chemical stresses in their environment.
S. K, T. Moural, Fang-Chao Zhu
semanticscholar   +1 more source

The catalytic role of glutathione transferases in heterologous anthocyanin biosynthesis

open access: yesNature Catalysis, 2023
Anthocyanins are used in the food and cosmetic industries. Due to the insufficient production in alternative hosts, they are still isolated from plants.
M. Eichenberger   +8 more
semanticscholar   +1 more source

Characterization of Neurospora crassa GH16, GH17, and GH72 gene families of cell wall crosslinking enzymes

open access: yesThe Cell Surface, 2022
GH16 chitin transferases, GH17 β-1,3-glucan transferases, and GH72 β-1,3-glucan/lichenin transferases are important fungal cell wall crosslinking enzymes.
Pavan Patel, Stephen J. Free
doaj   +1 more source

A Comparison of Dinoflagellate Thiolation Domain Binding Proteins Using In Vitro and Molecular Methods

open access: yesMarine Drugs, 2022
Dinoflagellates play important roles in ecosystems as primary producers and consumers making natural products that can benefit or harm environmental and human health but are also potential therapeutics with unique chemistries.
Ernest Williams   +2 more
doaj   +1 more source

Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis. [PDF]

open access: yesPLoS ONE, 2018
Bacillithiol is a low molecular weight thiol found in Firmicutes that is analogous to glutathione, which is absent in these bacteria. Bacillithiol transferases catalyze the transfer of bacillithiol to various substrates.
Varahenage R Perera   +4 more
doaj   +1 more source

Phosphoethanolamine Transferases as Drug Discovery Targets for Therapeutic Treatment of Multi-Drug Resistant Pathogenic Gram-Negative Bacteria

open access: yesAntibiotics, 2023
Antibiotic resistance caused by multidrug-resistant (MDR) bacteria is a major challenge to global public health. Polymyxins are increasingly being used as last-in-line antibiotics to treat MDR Gram-negative bacterial infections, but resistance ...
Van C. Thai   +3 more
doaj   +1 more source

Protein palmitoylation regulates osteoblast differentiation through BMP-induced osterix expression. [PDF]

open access: yesPLoS ONE, 2009
Osteoporosis is one of the most common diseases and can be treated by either anti-resorption drugs, anabolic drugs, or both. To search for anabolic drug targets for osteoporosis therapy, it is crucial to understand the biology of bone forming cells ...
Wai Fook Leong   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy