Results 11 to 20 of about 212,981 (331)
Plasmodium spp. membrane glutathione S-transferases: detoxification units and drug targets
Microbial Cell, 2014 Membrane glutathione S-transferases from the class of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) form a superfamily of detoxification enzymes that catalyze the conjugation of reduced glutathione (GSH) to a broad ...
Andreas Martin Lisewski
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BiomedicinesBackground/Objectives: The polypeptide N-acetylgalactosaminyltransferase (GALNT) family initiates mucin-type O-glycosylation, a post-translational modification that plays a pivotal role in cellular signaling, adhesion, and immune evasion.
Shruthi C. Iyer +2 more
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Glutathione Transferases [PDF]
The Arabidopsis Book, 2010 The 55 Arabidopsis glutathione transferases (GSTs) are, with one microsomal exception, a monophyletic group of soluble enzymes that can be divided into phi, tau, theta, zeta, lambda, dehydroascorbate reductase (DHAR) and TCHQD classes. The populous phi and tau classes are often highly stress inducible and regularly crop up in proteomic and ...
D. Dixon, R. Edwards
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The active site in class alpha glutathione transferases
, 1993 Sinning, I, +4 more
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Protein engineering to probe the catalytic mechanism of Alpha-class glutathione S-transferases
, 1997 Glutathione S-Transferases (GSTs) are a large family of isoenzymes that catalyse the addition of glutathione to hydrophobic electrophiles. Over-expression of GSTs in tumours leads to resistance to chemotherapy drugs, thus understanding GST biochemistry ...
Paul David. McDonagh (7656347)
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Glutathione Transferases as Efficient Ketosteroid Isomerases
Frontiers in Molecular Biosciences, 2021 In addition to their well-established role in detoxication, glutathione transferases (GSTs) have other biological functions. We are focusing on the ketosteroid isomerase activity, which appears to contribute to steroid hormone biosynthesis in mammalian ...
Bengt Mannervik +4 more
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Transferases in Polymer Chemistry [PDF]
, 2010 Transferases are enzymes that catalyze reactions in which a group is transferred from one compound to another. This makes these enzymes ideal catalysts for polymerization reactions.
Loos, Katja; id_orcid +4 more
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Biocatalysis for Biobased Chemicals
Biomolecules, 2013 The design and development of greener processes that are safe and friendly is an irreversible trend that is driven by sustainable and economic issues.
Rubén de Regil, Georgina Sandoval
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Hidden Glutathione Transferases in the Human Genome
Biomolecules, 2023 With the development of accurate protein structure prediction algorithms, artificial intelligence (AI) has emerged as a powerful tool in the field of structural biology. AI-based algorithms have been used to analyze large amounts of protein sequence data
Aaron J. Oakley
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Inhibitory effect of metals on animal and plant glutathione transferases.
Journal of Trace Elements in Medicine and Biology, 2020 Glutathione transferases (GSTs) represent a widespread enzyme superfamily in eukaryotes and prokaryotes catalyzing different reactions with endogenous and xenobiotic substrates such as organic pollutants.
Dirk Dobritzsch +4 more
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