Results 51 to 60 of about 10,076 (212)

Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from l-arabinose

Data in Brief, 2018
The dataset presented in this article is related to the research article entitled “One-pot, two-step transaminase and transketolase synthesis of l-gluco-heptulose from l-arabinose” (Bawn et al., 2018 in press) [1].
Maria Bawn, Fabiana Subrizi, Gary J. Lye, Tom D. Sheppard, Helen C. Hailes, John M. Ward   +5 more
doaj   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, Volume 49, Issue 7, Page 3543-3559, July 2026.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

New Role of Water in Transketolase Catalysis

, 2023
Transketolase catalyzes the interconversion of keto and aldo sugars. Its coenzyme is thiamine diphosphate. The binding of keto sugar with thiamine diphosphate is possible only after C2 deprotonation of its thiazole ring. It is believed that deprotonation
Olga N. Solovjeva
core   +1 more source

Peroxisomes and peroxisomal transketolase and transaldolase enzymes are essential for xylose alcoholic fermentation by the methylotrophic thermotolerant yeast, Ogataea (Hansenula) polymorpha

Biotechnology for Biofuels, 2018
Background Ogataea (Hansenula) polymorpha is one of the most thermotolerant xylose-fermenting yeast species reported to date. Several metabolic engineering approaches have been successfully demonstrated to improve high-temperature alcoholic fermentation ...
Olena O. Kurylenko, Justyna Ruchala, Roksolana V. Vasylyshyn, Oleh V. Stasyk, Olena V. Dmytruk, Kostyantyn V. Dmytruk, Andriy A. Sibirny   +6 more
doaj   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Cloning, expression and characterization of sugarcane (Saccharum officinarum L.) transketolase [PDF]

, 2013
Pentose phosphate pathway (PPP) composed of two functionally-connected phases, the oxidative and non-oxidative phase. Both phases catalysed by a series of enzymes.
Kalhori, Nahid, Go, Rusea, Nulit, Rosimah   +2 more
core   +1 more source

TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens

Diagnostic Pathology, 2008
In several tumors the transketolase activity, controlled inter alia by enzymes of the pentose phosphate pathway which is an alternative, energy generating reaction-cascade to glycolysis, has been correlated with proliferation.
Zabel Peter, Vollmer Ekkehard, Branscheid Detlev, Kähler Daniel, Schultz Holger, Goldmann Torsten   +5 more
doaj   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Chiral Bicomponent Melamine/Amino Acid Eutectogels: Efficient Catalysts for the Aldol Reaction

ChemSusChem, Volume 19, Issue 10, 27 May 2026.
Chiral bicomponent eutectogels were used as confined reaction media for stereoselective aldol reaction between cyclohexanone and p‐nitrobenzaldehyde, proving efficient and reusable catalysts. Supramolecular gels, characterized by reversibility, stimuli responsiveness, and high surface area, represent a promising class of materials in catalysis. In this
Salvatore Marullo, Paolo Reale, Francesca D’Anna   +2 more
wiley   +1 more source

Properties and functions of the thiamin diphosphate dependent enzyme transketolase [PDF]

, 1991
This review highlights recent research on the properties and functions of the enzyme transketolase, which requires thiamin diphosphate and a divalent metal ion for its activity.
Schenk, Gerhard, Duggleby, Ronald
core