Results 51 to 60 of about 10,904 (208)

Anaerobic Faecalicatena spp. degrade sulfoquinovose via a bifurcated 6-deoxy-6-sulfofructose transketolase/transaldolase pathway to both C2- and C3-sulfonate intermediates

Frontiers in Microbiology
Plant-produced sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose) is one of the most abundant sulfur-containing compounds in nature and its bacterial degradation plays an important role in the biogeochemical sulfur and carbon cycles and in all habitats where SQ
Sabrina Borusak, Sabrina Borusak, Sabrina Borusak, Karin Denger, Till Dorendorf, Till Dorendorf, Corentin Fournier, Corentin Fournier, Harry Lerner, Harry Lerner, Olga Mayans, Olga Mayans, Dieter Spiteller, Dieter Spiteller, David Schleheck, David Schleheck, David Schleheck   +16 more
doaj   +1 more source

Novel transaminases from thermophiles: from discovery to application

Microbial Biotechnology, 2022
Summary Transaminases (TAs) are promising biocatalysts for chiral amine synthesis; however, only few thermophilic TAs have been described to date. In this work, a genome mining approach was taken to seek novel TAs from nine thermophilic microorganisms ...
Max Cárdenas‐Fernández, Oliver Sinclair, John M. Ward   +2 more
doaj   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, Volume 7, Issue 5, October 2026.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source

Safety of benfotiamine as a Novel food pursuant to Regulation (EU) 2015/2283 and the bioavailability of benfotiamine as a source of thiamin in the context of Directive 2002/46/EC on food supplements

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of benfotiamine as a novel food (NF) pursuant to Regulation (EU) 2015/2283 and on the bioavailability of benfotiamine as a source of thiamin in the context of Directive 2002/46/EC ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Francesco Cubadda, Thomas Frenzel, Ursula Gundert‐Remy, Francesca Marcon, Harry J. McArdle, Monika Neuhäuser‐Berthold, Miguel Prieto Maradona, Alexandros Siskos, Matthew Wright, Gabriela Precup, Silvia Valtueña Martinez, Hanna Schmierer, Karen Ildico Hirsch‐Ernst   +27 more
wiley   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, Volume 13, Issue 51, 14 September 2026.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Overexpression of Plastid Transketolase in Tobacco Results in a Thiamine Auxotrophic Phenotype [PDF]

, 2015
To investigate the effect of increased plastid transketolase on photosynthetic capacity and growth, tobacco (Nicotiana tabacum) plants with increased levels of transketolase protein were produced.
FISK, Stuart, STITT, Mark, Stitt, M, Raines, CA, SULPICE, Ronan, Sulpice, R., LAWSON, Tracy, Khozaei, M., Lefebvre, SC, Gibon, Yves, Y., Fisk, S., Raines, C., Fisk, S, Lawson, T, Sulpice, R, LEFEBVRE, Stephane C, RAINES, Christine A, Khozaei, M, Gibon, Y, Gibon, Y., Stitt, M., GIBON, Yves, Lefebvre, S., KHOZAEI, Mahdi, Lawson, T.   +24 more
core   +1 more source

Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy

Diabetes & Vascular Disease Research, 2020
Thiamine prevents high glucose-induced damage in microvasculature, and progression of retinopathy and nephropathy in diabetic animals. Impaired thiamine availability causes renal damage in diabetic patients. Two single-nucleotide polymorphisms in SLC19A3
Elena Beltramo, Aurora Mazzeo, Tatiana Lopatina, Marina Trento, Massimo Porta   +4 more
doaj   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from l-arabinose

Data in Brief, 2018
The dataset presented in this article is related to the research article entitled “One-pot, two-step transaminase and transketolase synthesis of l-gluco-heptulose from l-arabinose” (Bawn et al., 2018 in press) [1].
Maria Bawn, Fabiana Subrizi, Gary J. Lye, Tom D. Sheppard, Helen C. Hailes, John M. Ward   +5 more
doaj   +1 more source

A review on research progress of transketolase [PDF]

Neuroscience Bulletin, 2009
Transketolase (TK), a thiamine diphosphate (ThDP)-dependent enzyme, catalyzes several key reactions of non-oxidative branch of pentose phosphate pathway. TK is a homodimer with two active sites that locate at the interface between the contacting monomers.
Jing, Zhao, Chun-Jiu, Zhong
openaire   +2 more sources