Results 71 to 80 of about 10,076 (212)

Mechanistic Studies of Escherichia Coli Transketolase

open access: yes, 2008
The enzyme transketolase is found in nature as part of the Pentose Phosphate Pathway to rearrange large sugar phosphates. It also is an important enzyme for carboncarbon bond formation for industrial biocatalysis.
Mathew Paul Martin (21819599)
core   +1 more source

Overexpression of Transketolase Relieves xylA Repression and Enhances Xylose Utilization in Saccharomyces cerevisiae During Mixed Sugar Fermentation

open access: yesGCB Bioenergy
Metabolic engineering of Saccharomyces cerevisiae has enabled xylose‐fermenting yeast strains. However, the bioavailability dilemma of xylose has become the core bottleneck restricting the economy of lignocellulose.
Si Xu   +5 more
doaj   +1 more source

Genetic Factors Associated with Toe Walking in Children

open access: yesВопросы современной педиатрии, 2020
The article describes genetic factors associated with toe walking in children. Association of gait abnormality with variants in genes listed below is shown: PMP22 (peripheral myelin protein 22), EGR2 (early growth response protein 2), AIFM1 (apoptosis ...
David Pomarino   +4 more
doaj   +1 more source

How to Enhance the Applicability of Metal Ion Affinity‐bound Biocatalysts? Comprehensive Overview and Case Study With a Phenylalanine Ammonia Lyase and an Amine Transaminase

open access: yesChemBioChem, Volume 27, Issue 8, April 2026.
Co2+‐charged EDTA‐based affinity function on various supports enabled metal ion affinity immobilization of a phenylalanine ammonia‐lyase (PcPAL) or an amine transaminase (VfTA). The best PcPAL forms were stable in reactions performed in 6M ammonia. Recharging the magnetic nanoparticle (MNP) form of PcPAL or VfTA after diethylenetriamine elution and ...
Máté Laurinyecz   +7 more
wiley   +1 more source

Akt phosphorylates transketolase : : regulatory step of de novo purine synthesis [PDF]

open access: yes, 2013
Akt is a major regulatory protein involved in many cellular processes, particularly cell growth, proliferation, and progression. The objective of this study is to elucidate Akt regulation of de novo purine synthesis. Rates of de novo purine synthesis and
Phan, Tony Minh
core  

Genome‐wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

open access: yesmLife, Volume 5, Issue 2, Page 180-198, April 2026.
Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei   +9 more
wiley   +1 more source

Chaetocin, a Natural Inhibitor of Transketolase, Suppresses the Non-Oxidative Pentose Phosphate Pathway and Inhibits the Growth of Drug-Resistant Non-Small Cell Lung Cancer

open access: yesAntioxidants
Worldwide, lung cancer is the most common cause of cancer-related death, which is made worse by the development of drug resistance during treatment. It is urgent to develop new therapeutic methods and small molecule drugs for tumor resistance. Chaetocin,
Song Li   +7 more
doaj   +1 more source

Development of a Novel Assay for Synthesis and Hydrolysis of Sedoheptulose 1,7-bisphosphate (SBP) in vitro by Combinations of Purified Fructose 1,6-bisphosphate aldolases (FBA) Proteins and Fructose 1,6-bisphosphatases (FBPase) Proteins from Bacillus methanolicus MGA3

open access: yesBio-Protocol, 2014
Bacillus methanolicus (B. methanolicus) is a Gram-positive, thermotolerant, and facultative methylotrophic bacterium that can use the one-carbon (C1) compound methanol as a source of carbon and energy (Schendel et al., 1990; Arfman et al., 1997; Arfman ...
Jessica Stolzenberger   +4 more
doaj   +1 more source

Gut Luminal Exosomes in Young and Old Mice: Multi‐Omic Characteristics and Regulation of Gut Permeability

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
This graphical abstract shows that gut luminal exosomes (LFEs) change with aging, with old mice producing LFEs that disrupt gut barrier integrity, alter microbiome composition, and promote insulin resistance. In contrast, LFEs from young mice improve gut barrier function and metabolic health, and transferring these LFEs can partially reverse age ...
Abdelnaby Khalyfa   +3 more
wiley   +1 more source

Progress on the role of transketolase in occurrence and treatment of diabetes and its complications [PDF]

open access: yesJichu yixue yu linchuang
Transketolase (TKT) is an important enzyme that catalyzes the non-oxidative phase group transfer reaction of pentose phosphate pathway (PPP), and is involved in the metabolism of various energy substances in the body, such as glucose, ribose, nucleotides
WANG Zeying, LIU Zhi, TAI Yu, YANG Zhongbin, SU Yan
doaj   +1 more source

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