Results 71 to 80 of about 16,581 (212)

Data on a thermostable enzymatic one-pot reaction for the production of a high-value compound from l-arabinose

Data in Brief, 2018
The dataset presented in this article is related to the research article entitled “One-pot, two-step transaminase and transketolase synthesis of l-gluco-heptulose from l-arabinose” (Bawn et al., 2018 in press) [1].
Maria Bawn, Fabiana Subrizi, Gary J. Lye, Tom D. Sheppard, Helen C. Hailes, John M. Ward   +5 more
doaj   +1 more source

Probing the Cancer Mutational Landscape of KMT2 Regulatory Subunits

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Pipeline to characterize the KMT2 cancer mutational landscape starts with querying genomic databases (top left) for mutations mapping to ASH2L, RbBP5, WDR5, and DPY‐30. Subsequent steps include the expression of these mutants in cell (bottom left), their systemic purification and biochemical characterization using isothermal titration calorimetry ...
Sabrina Grégoire, Sara Chow, Monika Joshi, Pamela Zhang, Aws Almir Ahmad, Ashley Janna, Veronique Tremblay, Marcelo Muñoz, Arvind Mer, Jean‐Francois Couture   +9 more
wiley   +1 more source

Peroxisomes and peroxisomal transketolase and transaldolase enzymes are essential for xylose alcoholic fermentation by the methylotrophic thermotolerant yeast, Ogataea (Hansenula) polymorpha

Biotechnology for Biofuels, 2018
Background Ogataea (Hansenula) polymorpha is one of the most thermotolerant xylose-fermenting yeast species reported to date. Several metabolic engineering approaches have been successfully demonstrated to improve high-temperature alcoholic fermentation ...
Olena O. Kurylenko, Justyna Ruchala, Roksolana V. Vasylyshyn, Oleh V. Stasyk, Olena V. Dmytruk, Kostyantyn V. Dmytruk, Andriy A. Sibirny   +6 more
doaj   +1 more source

Gut Luminal Exosomes in Young and Old Mice: Multi‐Omic Characteristics and Regulation of Gut Permeability

Aging Cell, Volume 25, Issue 4, April 2026.
This graphical abstract shows that gut luminal exosomes (LFEs) change with aging, with old mice producing LFEs that disrupt gut barrier integrity, alter microbiome composition, and promote insulin resistance. In contrast, LFEs from young mice improve gut barrier function and metabolic health, and transferring these LFEs can partially reverse age ...
Abdelnaby Khalyfa, Lyu Zhen, Trupti Joshi, David Gozal   +3 more
wiley   +1 more source

TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens

Diagnostic Pathology, 2008
In several tumors the transketolase activity, controlled inter alia by enzymes of the pentose phosphate pathway which is an alternative, energy generating reaction-cascade to glycolysis, has been correlated with proliferation.
Zabel Peter, Vollmer Ekkehard, Branscheid Detlev, Kähler Daniel, Schultz Holger, Goldmann Torsten   +5 more
doaj   +1 more source

The response of diatom central carbon metabolism to nitrogen starvation is different from that of green algae and higher plants [PDF]

, 2011
The availability of nitrogen varies greatly in the ocean and limits primary productivity over large areas. Diatoms, a group of phytoplankton that are responsible for about 20% of global carbon fixation, respond rapidly to influxes of nitrate and are ...
Hockin, Nicola Louise, Kopriva, Stanislav, Malin, Gill, Mock, Thomas, Mulholland, Francis   +4 more
core   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana [PDF]

, 2018
Transketolase (TKT) is part of the non-oxidative branch of the pentose phosphate pathway (PPP). Here we describe the impact of removing this enzyme from the pathogenic protozoan Leishmania mexicana.
A Chokkathukalam, A Garami, A Garami, A Lal, A Misslitz, A Mukherjee, A Seyfang, A Stincone, Andrew W. Pountain, AT Cordeiro, B Giardine, B Langmead, B Raz, BM Bakker, C Trapnell, CN Cronin, D Rodriguez-Contreras, D Rodriguez-Contreras, DA Maugeri, DA Maugeri, David Wildridge, DH Kim, DJ Creek, DJ Creek, DJ Creek, DT Hart, E Afgan, E Tetaud, EC Saunders, EC Saunders, EJ Kerkhoven, F Achcar, Fiona Achcar, FP Keegan, Frédéric Bringaud, GB Moorhead, IM-J Xu, J Faria, J Kloehn, J Kovarova, J Xia, JE Ralton, JR Dusick, Julie Kovářová, K Leifso, L Wu, M Silverberg, MA Comini, MB Hughes, MG De Vas, Michael P. Barrett, MJ McConville, NJ Veitch, P Kaye, PA Bates, PA Michels, PJ Alcolea, PJ Alcolea, R Bais, R Mancilla, RA Scheltema, RH Villet, Richard J. S. Burchmore, RJ Burchmore, RJ Kleijn, S Allmann, S Langbein, S Weidt, SA Stoffel, SH Lee, Stefan Weidt, T Naderer, T Naderer, Thomas Naderer, TR Holzer, W Moreira, WI Staiger, WN Lee, Z Lobo   +78 more
core   +10 more sources

CO2-Induced Transcriptional Reorganization: Molecular Basis of Capnophillic Lactic Fermentation in Thermotoga neapolitana [PDF]

, 2020
Capnophilic lactic fermentation (CLF) is a novel anaplerotic pathway able to convert sugars to lactic acid (LA) and hydrogen using CO2 as carbon enhancer in the hyperthermophilic bacterium Thermotoga neapolitana.
Dipasquale, Laura, d’Ippolito, Giuliana, ESERCIZIO, NUNZIA, Fontana, Angelo, LANDI, SIMONE, Lanzilli, Mariamichella, Pradhan, Nirakar, VASTANO, MARCO   +7 more
core   +2 more sources

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2541-2558, April 2026.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes, Omar Sandoval‐Ibáñez, Stéphanie Arrivault, David Rolo, F. Vanessa Loiacono, Alexander Erban, Daniel Karcher, Stephan Obst, Stephanie Ruf, Joachim Kopka, Ralph Bock   +10 more
wiley   +1 more source