Results 91 to 100 of about 10,076 (212)

Rational substrate and enzyme engineering of transketolase for aromatics [PDF]

, 2012
The uses of 3-formylbenzoic acid and 4-formylbenzoic acid as molecular probes along with previous and new transketolase mutants revealed the factors governing the rate of reaction between transketolase and aromatic aldehydes.
Dalby, PA, Payongsri, P, MacMurray, A, Steadman, D, Strafford, J, Hailes, HC   +5 more
core  

Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation.

PLoS ONE, 2019
Neutrophil extracellular traps (NETs) are a recently identified, web-like, extracellular structure composed of decondensed nuclear DNA and associated antimicrobial granules.
Donporn Riyapa, Darawan Rinchai, Veerachat Muangsombut, Chayanin Wuttinontananchai, Mohammed Toufiq, Damien Chaussabel, Manabu Ato, Jenefer M Blackwell, Sunee Korbsrisate   +8 more
doaj   +1 more source

Kinetics of reconstruction of holo‐transketolase [PDF]

FEBS Letters, 1975
Kochetov, G.A., Philippov, P.P., Razjivin, A.P., Tikhomirova, N.K.   +3 more
openaire   +2 more sources

Interactions with hemoglobin: A source of error in measurements of transketolase activity in hemolysates

, 1989
Measurements of the activity of transketolase in human erythrocyte lysates by an assay coupled to NADH oxidation indicate that interactions of assay substrates with hemoglobin can give rise to overestimations of transketolase activity.
Nixon P.F., Waltham M., Ioannoni B., Price J., Grudzinski A.   +4 more
core   +1 more source

Mechanism-Based Studies of the Active Site-Directed Inhibition and Activation of Enzyme Transketolase [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1988
Derivatives of phenyl-keto butenoic acids have been reported to be inhibitors of pyruvate decarboxylase, (PDC). The inhibition of transketolase, a thiamine requiring enzyme such as PDF, by meta nitrophenyl derivative of 2-oxo-3-butenoic acid (MNPB) is ...
Bijan Farzami
doaj  

The production and use of transketolase as a catalyst for carbon-carbon bond formation [PDF]

, 1994
This thesis describes the advances made towards the development of a complete pilot scale process for an enzyme catalysed carbon-carbon bond forming reaction.
Hobbs, Gordon Robert
core  

Comparison of transketolase model with crystal structure.

, 2012
A) Superimposition of the homology model of human transketolase (in pink) with the recently released crystal structure (in white). B) Close view of the residues used for pharmacophore definition, in the homology model (in pink and thin residues) and in ...
Cristian Obiol-Pardo (179509), Jaime Rubio-Martinez (179518), Gema Alcarraz-Vizán (179513), Marta Cascante (67954)   +3 more
core   +1 more source

In vitro phosphorylation of purified transketolase by protein kinase C

, 1996
Catalytically active transketolase was purified from rat liver cytosolic fraction by more than 120-fold to near homogeneity by successive column chromatography using DEAE-Sephacel, hydroxylapatite and Mono P matrices.
Kyu Shik Jeong, Yun Jo Soh
core  

PREPARATION AND PROPERTIES OF TRANSKETOLASE FROM PORK LIVER

, 1960
Transketolase of pork liver has been purified 90-fold and separated from ribulose 5-phosphate 3-epimerase. The transketolase is most stable between pH 7.5 and 8.5 and below 40 °C. The pH range for optimum activity is between 7.6 and 8.1.
F. J. Simpson
core   +1 more source

Biosynthesis of the benzylpyrrolidine precursor in anisomycin by a unique ThDP-dependent enzyme

Synthetic and Systems Biotechnology
Anisomycin (compound 1), a multifunctional pyrrolidine antibiotic, primarily inhibits protein biosynthesis by binding to the ribosome. Upon binding to the ribosome, the para-phenol moiety of anisomycin inserts completely into the hydrophobic crevice of ...
Yongjian Qiao, Junbo Wang, Dashan Zhang, Xiaoqing Zheng, Baixin Lin, Yongkang Huang, Yulin Liao, Zixin Deng, Lingxin Kong, Delin You   +9 more
doaj   +1 more source