Results 61 to 70 of about 10,076 (212)
ABSTRACT SARS‐CoV‐2 infection is linked to persistent neurological symptoms Post‐Acute Sequelae SARS‐CoV‐2 (neuro‐PASC) and elevated risk of neurodegenerative disease, but molecular events connecting acute viral injury to long‐term CNS dysfunction remain unclear.
Gunjan Bawne +4 more
wiley +1 more source
Isolation of transketolase gene, subcellular localization, and transketolase protein structure studies of sugarcane (Saccharum officinarum. L) [PDF]
This study focused on isolation, identification, subcellular localisation, protein structure prediction of transketolase enzyme from sugarcane, Saccharum officinarum.
Kalhori, Nahid
core
Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles
Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan +8 more
wiley +1 more source
Transketolase structure model.
A) Homology model of human transketolase showing the antiparallel alpha helices involved in dimerization. B) Close view of the alpha helix D200-G210 showing the selected residues of the 5-point pharmacophore.
Cristian Obiol-Pardo (179509) +3 more
core +1 more source
Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Josefin Engelhardt +6 more
doaj +1 more source
Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents
Transketolase (TK) has been previously engineered, using semi-rational directed evolution and substrate walking, to accept increasingly aliphatic, cyclic, and then aromatic substrates.
Phattaraporn Morris +3 more
doaj +1 more source
Metabolism Controls the Timing of Human Brain Development and Maturation
ABSTRACT Among primates the human brain is the largest in size, exhibiting a higher neuronal density and connectivity. The prolonged expansion and subsequent connectome reorganization of the human brain have been suggested to promote higher cognitive and behavioral abilities.
Valentina Rava +3 more
wiley +1 more source
Molecular modeling and simulation of transketolase from orthosiphon stamineus
Background: Orthosiphon stamineus is a traditional medicinal plant in Southeast Asia countries with various well-known pharmacological activities such as antidiabetic, diuretics and antitumor activities. Transketolase is one of the proteins identified in
Ng, Mei Ling +2 more
core +1 more source
Probing the Cancer Mutational Landscape of KMT2 Regulatory Subunits
Pipeline to characterize the KMT2 cancer mutational landscape starts with querying genomic databases (top left) for mutations mapping to ASH2L, RbBP5, WDR5, and DPY‐30. Subsequent steps include the expression of these mutants in cell (bottom left), their systemic purification and biochemical characterization using isothermal titration calorimetry ...
Sabrina Grégoire +9 more
wiley +1 more source
Directed evolution of transketolase, a carbon-carbon forming enzyme.
The enzyme transketolase (Enzyme Commission number: 2.2.1.1) has significant potential as a biocatalyst in the production of pharmaceuticals and fine chemicals.
Miller, O.J.
core

