Results 81 to 90 of about 19,401 (288)
Systematic Review of the Huntington's Disease Drug Development Pipeline, 2014 to 2025
Movement Disorders, EarlyView.Abstract Background In the past decade, significant advances have improved our understanding of the mechanisms underlying HD pathobiology leading to several putative therapeutic targets for HD. Objective The aim was to describe the Huntington's disease (HD) drug development clinical pipeline.
Pavlina Konstantinova +5 more
wiley +1 more source
Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency [PDF]
Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adolescents with ...
Mehmet Ağıllı +5 more
core +1 more source
Nutrition in Clinical Practice, EarlyView.Abstract Preoperative parenteral nutrition (PN) improves outcomes in malnourished surgical patients. Traditionally, this requires hospital admission, increasing length of stay and costs—challenges worsened by limited hospital bed availability. Outpatient PN may offer a feasible alternative.
Narisorn Lakananurak, Leah Gramlich
wiley +1 more source
Frontiers in NutritionObjectiveThiamine deficiency is a common complication in end-stage renal disease (ESRD) patients receiving maintenance hemodialysis (HD). The purpose of this cross-sectional study was to assess the prevalence of thiamine deficiency in HD patients and its
Bo Yang +7 more
doaj +1 more source
GmPGL1, a Thiamine Thiazole Synthase, Is Required for the Biosynthesis of Thiamine in Soybean
Frontiers in Plant Science, 2019 Thiamine is an essential cofactor in several enzymatic reactions for all living organisms. Animals cannot synthesize thiamine and depend on their diet.
Xingxing Feng +11 more
doaj +1 more source
Effect of thiamine deficiency on canine gastric secretion of acid
, 1959 A study was undertaken to determine the effect of thiamine deficiency on the hydrochloric acid output of vagally denervated gastric pouches (Heidenhain-type) and vagally innervated gastric pouches (Pavlov-type) in dogs.
Marjorie K. Lavers +2 more
core +1 more source
EEG findings in SERAC1‐related MEGD(H)EL syndrome
Epileptic Disorders, EarlyView.
Apurva Patel, Dalila Lewis, Thomas Koch
wiley +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Thiamine (Vitamin B1) Deficiency (Presentation)
, 2023 Overview of thiamine deficiency and its neuro-ophthalmic manifestations with an illustrative case example and discussion of clinical presentation, relevant biochemistry, testing, risk factors, and treatment.
Nirupama Devanathan; Devin D. Mackay, MD
core
Thiamine transporter-2 deficiency: outcome and treatment monitoring [PDF]
, 2014 [Background] The clinical characteristics distinguishing treatable thiamine transporter-2 deficiency (ThTR2) due to SLC19A3 genetic defects from the other devastating causes of Leigh syndrome are sparse.[Methods] We ...
Ortigoza-Escobar, Juan Darío +19 more
core +1 more source