Results 241 to 250 of about 36,745 (354)

The International Scientific Forum on Alcohol Research (ISFAR) critiques of alcohol research: Promoting health benefits and downplaying harms

open access: yesAddiction, Volume 120, Issue 11, Page 2319-2328, November 2025.
Abstract Background and Aims The International Scientific Forum on Alcohol Research (ISFAR), many of whose members are linked to the alcohol industry, has published over 280 critiques on alcohol and health research. This study investigated whether ISFAR critiques favour studies reporting alcohol's health benefits while being more critical of those ...
James M. Clay   +7 more
wiley   +1 more source

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

open access: yesThe American Journal on Addictions, Volume 34, Issue 6, Page 589-602, November 2025.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi   +4 more
wiley   +1 more source

Perinatal thiamine deficiency causes cochlear innervation abnormalities in mice [PDF]

open access: green, 2016
Stéphane F. Maison   +3 more
openalex   +1 more source

Structure‐based discovery of thiamine uptake inhibitors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel   +2 more
wiley   +1 more source

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