Results 91 to 100 of about 330,726 (289)

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

open access: yesAdvanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin   +4 more
wiley   +1 more source

Surgical site infections after sarcoma resections in the peripelvic region: do we need perioperative antibiotic prophylaxis?

open access: yesFrontiers in Oncology
IntroductionSurgical site infections (SSI) are one of the most common complications after extensive sarcoma resections and represent a daily challenge. SSI occur in up to 50% of cases particularly in the peripelvic area.
Alexander Klein   +10 more
doaj   +1 more source

Association between insulin resistance, lean mass and muscle torque/force in proximal versus distal body parts in healthy young men [PDF]

open access: yes, 2014
Objectives:The purpose of this study was to investigate whether there is already an association of insulin resistance (IR) with muscle mass and –force/torque in an adult population and whether this relationship is the same in distal and proximal body ...
Calders, Patrick   +7 more
core   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

open access: yesAdvanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong   +11 more
wiley   +1 more source

Using a Second Order Sigma-Delta Control to Improve the Performance of Metal-Oxide Gas Sensors [PDF]

open access: yes, 2018
Controls of surface potential have been proposed to accelerate the time response of MOX gas sensors. These controls use temperature modulations and a feedback loop based on first-order sigma-delta modulators to keep constant the surface potential ...
Domínguez Pumar, Manuel   +4 more
core   +3 more sources

Comparing Donor Site Morbidity for Autologous Breast Reconstruction: Thigh vs. Abdomen

open access: gold, 2022
Z-Hye Lee   +6 more
openalex   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

open access: yesAdvanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen   +11 more
wiley   +1 more source

Temperature-driven volume transition in hydrogels: phase--coexistence and interface localization

open access: yes, 2016
We study volume transition phenomenon in hydrogels within the framework of Flory-Rehner thermodynamic modelling; we show that starting from different models for the Flory parameter different conclusions can be achieved, in terms of admissible coexisting ...
Cirillo, Emilio N. M.   +2 more
core   +4 more sources

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

open access: yesAdvanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang   +14 more
wiley   +1 more source

Massive tubercular pseudo-tumor of the thigh: a case report

open access: yesThe Pan African Medical Journal, 2012
Psoas abscess in cases of tuberculosis originates from the primary lesion in the lower dorsal or the lumbar spine. From the spinal origin of the Psoas muscle, this abscess tracks down its sheath and may be palpable in the iliac fossa, in the lumbar ...
Bhavuk Garg   +3 more
doaj   +1 more source

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