Results 81 to 90 of about 319,971 (284)

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience

대한영상의학회지, 2021
Purpose This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE.
Junghoon Kim, Jeong Ah Ryu, Juhan Lee
doaj   +1 more source

A Cadaveric Study on the Variation in the Level of Division of Sciatic Nerve in Nepalese Population

Journal of Nobel Medical College, 2020
Background: Sciatic nerve, the thickest nerve of our body (around 2cm wide at its origin), leaves the pelvic cavity from the greater sciatic foramina below the piriformis muscle and between the greater trochanter of femur and ischial tuberosity.
Diwakar Kumar Shah, Sanzida Khatun
doaj   +1 more source

Vertical rectus abdominis myocutaneous versus alternative flaps for perineal repair after abdominoperineal excision of the rectum in the era of laparoscopic surgery [PDF]

, 2017
Aims: Plastic surgical reconstruction of the perineum is often required after abdominoperineal excision of the rectum. Options for this reconstruction include a vertical rectus abdominis myocutaneous (VRAM) flap, gluteal fasciocutaneous flap, and ...
Johnstone, Mark Scott
core   +1 more source

Bioinspired Hierarchical Architecture with Water Transport Channels for Strong Adhesion at the Sweating Interface

Advanced Science, EarlyView.
To address adhesion failure in sweaty epidermal electronics, this study proposes a cross‐species, multi‐scale biomimetic interface. By modeling staged wet adhesion, it integrates self‐regulating liquid bridges with directional drainage. This design ensures stable, high‐performance flexible sensing in complex physiological environments, offering a ...
Jieliang Zhao, Yu Xiang, Heng Wang, Huiqing Xu, Zhong Liu, Lulu Liang, Fengwen Jiang, Xuemei Chen, Wenzhong Wang, Chenqing Liu, Guodong Liu, Shaoze Yan, Xu Hou   +12 more
wiley   +1 more source

Role of peripheral quantitative computed tomography in identifying disuse osteoporosis in paraplegia [PDF]

, 2009
Objective: Disuse osteoporosis is a major long-term health consequence of spinal cord injury (SCI) that still needs to be addressed. Its management in SCI should begin with accurate diagnosis, followed by targeted treatments in the most vulnerable ...
A Frotzler, A Frotzler, AA Freehafer, Alan N. McLean, B Chen, David B. Allan, ED Bruin de, HH Bolotin, HM Frost, J Rittweger, JL Ferretti, L Giangregorio, L Maimoun, M Bélanger, P Eser, P Eser, P Eser, P Frey-Rindova, P Vestergaard, S Dudley-Javoroski, S-D Jiang, Sylvie Coupaud, T Mohr   +22 more
core   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Surgical site infections after sarcoma resections in the peripelvic region: do we need perioperative antibiotic prophylaxis?

Frontiers in Oncology
IntroductionSurgical site infections (SSI) are one of the most common complications after extensive sarcoma resections and represent a daily challenge. SSI occur in up to 50% of cases particularly in the peripelvic area.
Alexander Klein, Chataut Chudamani, Andreas Wieser, Andreas Wieser, Andreas Wieser, Andreas Wieser, Sophia S. Goller, Luc M. Berclaz, Dorit Di Gioia, Boris M. Holzapfel, Hans Roland Dürr   +10 more
doaj   +1 more source

Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration

Advanced Science, EarlyView.
Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li, Hao Zhang, Lingtong Sun, Yingfeng Su, Yang Xu, Jian Huang, Jingchao Wen, Jinjin Zhu, Jianjun Ma, Wenbin Xu   +9 more
wiley   +1 more source

Association between insulin resistance, lean mass and muscle torque/force in proximal versus distal body parts in healthy young men [PDF]

, 2014
Objectives:The purpose of this study was to investigate whether there is already an association of insulin resistance (IR) with muscle mass and –force/torque in an adult population and whether this relationship is the same in distal and proximal body ...
Calders, Patrick, Cambier, Dirk, Goemaere, Stefan, Gysel, Tineke, Kaufman, Jean, Roman de Mettelinge, Tine, Taes, Youri, Zmierczak, Hans-Georg   +7 more
core   +1 more source