Results 91 to 100 of about 198,238 (303)
Free anterolateral thigh flaps for upper extremity soft tissue reconstruction
, 2015 Introduction: Limb-threatening wounds of the upper extremity pose a challenge to the micro vascular surgeon. The aim of this study is to analyze the outcome of free anterolateral thigh flaps for upper extremity soft tissue reconstruction.Methods: A ...
Al-Benna, S +13 more
core +1 more source
Advanced Science, EarlyView.Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang +11 more
wiley +1 more source
Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic
Angewandte Chemie, EarlyView.To enable incorporation of l‐2‐aminodecanoic acid into polymyxin by fermentation, a single Trp‐to‐Ala substitution is rationally introduced into the adenylation‐domain residue of its nonribosomal peptide synthetase (NRPS) and efficiently switches substrate selectivity. The engineered strain produces biologically active Ada‐polymyxin, demonstrating that
Maximilian Müll +7 more
wiley +2 more sources
Primitive hydatic cyst of the thigh. About a case
La Revue Marocaine de Chirurgie Orthopédique et Traumatologique (RMACOT)Hydatid echinococcosis is preferentially localized to the liver. Muscular localization is very rare, representing less than 1%. The symptoms are often discreet and the diagnosis is confirmed by imaging: ultrasound and/or magnetic resonance imaging, thus
Mohammed Sbihi +8 more
doaj +1 more source
대한영상의학회지, 2021 Purpose This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE.
Junghoon Kim, Jeong Ah Ryu, Juhan Lee
doaj +1 more source
Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair
Advanced Science, EarlyView.Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou +14 more
wiley +1 more source
Bone & Joint ResearchAims: Anterior cruciate ligament reconstruction (ACLR) is associated with persistent strength deficits and thigh muscle atrophy, which may contribute to post-traumatic osteoarthritis (PTOA). Other potential musculoskeletal alterations, such as changes in
Karl Morgan +9 more
doaj +1 more source
Objective: This study investigated the reconstruction of multiple long digital and hand defects using the multilobed anterolateral thigh perforator flap.
Chao Ma +5 more
core +1 more source
Accuracy of Posture Allocation Algorithms for Thigh- and Waist-Worn Accelerometers [PDF]
, 2016 The objective of this study is to compare the accuracy of the activPAL and ActiGraph GT3X+ (waist and thigh) proprietary postural allocation algorithms and an open-source postural allocation algorithm applied to GENEActiv (thigh) and ActiGraph GT3X ...
Charlotte L. Edwardson (7152536) +36 more
core +1 more source
TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma
Advanced Science, EarlyView.TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin +9 more
wiley +1 more source