Results 91 to 100 of about 33,429 (217)
A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells
Advanced Science, EarlyView.A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong +13 more
wiley +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Thin Layer Chromatography in Environmental Analysis
Reviews in Analytical Chemistry, 1995 Sherma, Joseph
doaj +1 more source
Optimization of SWCNT‐FET Biosensors by Aptamer Engineering and Toehold‐Mediated Strand Displacement
Advanced Science, EarlyView.Aptamer‐based single‐walled carbon nanotube (SWCNT) field‐effect transistor (FET) biosensors are developed for label‐free, real‐time biomarker detection. Truncated DNA aptamers enhance sensitivity through improved conformational switching. A toehold‐mediated strand displacement (TMSD) strategy optimizes functionalization and simplifies fabrication. The
Haosen Miao +8 more
wiley +1 more source
Advanced Science, EarlyView.Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin +9 more
wiley +1 more source
Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity
Advanced Science, EarlyView.This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao +10 more
wiley +1 more source
Quantitative Thin Layer Chromatography Analysis by Photodensitometry
Reviews in Analytical Chemistry, 2002 Cimpoiu, Claudia, Hodisan, Sorin
doaj +1 more source
Advanced Science, EarlyView.Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao +25 more
wiley +1 more source