Results 211 to 220 of about 129,123 (262)

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu   +10 more
wiley   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

Cu─O─Al Interfacial Engineering on Cu Nanowires for Durable CO2 Electroreduction Into Multi‐Carbon Products

open access: yesAdvanced Science, EarlyView.
A Cu nanowire/AlOx core‐shell catalyst is reported for CO2 electroreduction. Acting as a Lewis acid, the AlOx shell not only stabilizes Cu+ species at the Cu─O─Al interface but also creates an alkaline local microenvironment via *OH adsorption. This dual functionality stabilizes the catalyst structure while promoting the C─C coupling process, resulting
Xiaodong Liu   +7 more
wiley   +1 more source

Sabatier‐Adjusted d‐Band Centers of Scalable Asymmetric Iron Sites toward Dynamic Nonradical Network for Fast Mineralization with Low‐Amount Oxidant

open access: yesAdvanced Science, EarlyView.
Asymmetric iron single‐atom catalysts with Sabatier‐adjusted d‐band centers overcome the inherent limitations of peroxymonosulfate (PMS) activation by establishing a synergistic nonradical pathway network, achieving exceptional pollutant mineralization (≈85%) at only one‐tenth conventional PMS dosage.
Yue Chen   +10 more
wiley   +1 more source

Compound Identification in Thin-Layer Chromatography Using Spectrometric Methods

open access: yesReviews in Analytical Chemistry, 1997
Gocan, S., Cimpan, G.
doaj   +1 more source

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