Results 231 to 240 of about 319,292 (343)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

An Advanced High‐Performance Ultrafast Ammonium‐Ion Aqueous Battery Based on Dual‐Metal Redox Open Framework Molecular Magnet

open access: yesAdvanced Science, EarlyView.
The Prussian Blue Analogue molecular magnet KMnFeHCF is demonstrated as a high‐performance cathode for ultra‐fast aqueous ammonium‐ion batteries. A full cell using KMnFeHCF and graphite delivers ~71 mAh g−1 at 1.25 A g−1 and ~51 mAh g−1 at 2.2 A g−1, retaining 50% capacity after 1850 cycles. Its scalability, cycling stability, and low cost offer strong
Nilasha Maiti   +5 more
wiley   +1 more source

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

open access: yesAdvanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen   +4 more
wiley   +1 more source

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