Results 101 to 110 of about 3,024,368 (359)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Thinking Skills and Creativity JournalThe importance of using learning media in mathematics learning so that learning is more interesting has not been optimized, learning is still conventional which affects the low ability to solve students' mathematical problems.
Kadek Ayu Mutiara Pratiwi +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Fostering critical thinking skills: A strategy for enhancing evidence based wellness care
, 2005 Methods: This case study describes how health may be promoted and disease prevented through development of personalized wellness programs. As critical thinking is essential to the provision of evidence based wellness care, diverse learning opportunities ...
Jamison, J.R., Jennifer R Jamison
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Pedagogical methodologies in teaching critical thinking skills to basic police recruits at Madison Area Technical College [PDF]
, 2000 Plan BPolice officers working in the year 2000 have a much different job than those working a few short years ago. In the 1960s, despite the threat of faster response times and more officers on the street, crime rates continued to rise.
Pace, Jack David
core
, 2023 This study focuses on the effect of using postmodern tale films, which are based on the transformation of a text and enable multiple reading, as an educational tool on critical thinking and media literacy skills.
BAŞ, Bayram, Baş, B., Ulu-Aslan, Emine
core +1 more source
Computers and Education: Artificial Intelligence, 2023 Ramazan Yılmaz, F. Yılmaz
semanticscholar +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source