Results 121 to 130 of about 1,235,921 (309)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Zhongyong Thinking Style and Resilience Capacity in Chinese Undergraduates: The Chain Mediating Role of Cognitive Reappraisal and Positive Affect. [PDF]

Front Psychol, 2022
Zhou S, Li X.
europepmc   +1 more source

AN APPLICATION OF LEARNING STYLE THEORY TO UNDERGRADUATE INSTRUCTION IN ACCOUNTING: A MINNESOTA EXAMPLE [PDF]

This paper reports the results of a student learning style inventory by Flemming and Miller. The survey was used in an introductory accounting course in addition to other curriculum materials to foster critical thinking.
Nefstead, Ward E.
core   +1 more source

Pengaruh Pembelajaran Kontekstual dan Gaya Berpikir terhadap Hasil Belajar Sosiologi [PDF]

, 2016
This study aims at discovering the learning outcome of the students using CTL and conventional learning strategy and also to investigate the learning outcome of sociology among the students who possess a divergent and convergent thinking style.
Makulua, I. J. (Izak), Sulton, S. (Sulton), Toenlioe, A. J. (Anselmus)   +2 more
core  

Kesan gaya berfikir dan kemahiran penyelesaian masalah inventif terhadap kemahiran penyelesaian masalah [PDF]

, 2020
The Critical and Creative Thinking Skills Model (CCTS) aims to adopt critical and creative thinking skills among students in order to solve problems effectively.
Sai’en, Shanty
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Teasing and Internet Harassment among Adolescents: The Mediating Role of Envy and the Moderating Role of the Zhong-Yong Thinking Style. [PDF]

Int J Environ Res Public Health, 2022
Wang Q, Tu R, Jiang Y, Hu W, Luo X.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The Influence of Intuitive Thinking Styles Versus Analytical Thinking Styles on the Use of Stereotypes in Judgments [PDF]

, 2012
Participants were randomly assigned to receive one of two instruction sets, one which encouraged them to rely on their intuitions and another which encouraged a more analytical thinking style.
Cowgill, Colleen
core