Results 111 to 120 of about 1,235,921 (309)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

An Evaluation of the Belief in Science Scale

open access: yesFrontiers in Psychology, 2019
The Belief in Science Scale (BISS) is a unidimensional measure that assesses the degree to which science is valued as a source of superior knowledge.
Neil Dagnall   +3 more
doaj   +1 more source

Analisis Miskonsepsi Siswa Pada Materi Pokok Lingkaran Ditinjau Dari Kesiapan Belajar Dan Gaya Berpikir Siswa Kelas XI IPA SMA N 3 Surakarta Tahun Ajaran 2013/2014 [PDF]

open access: yes, 2016
The purposes of this research were: (1) knowing the characteristics of the misconception, and (2) knowing the causes of the misconception of the XI grade students in the academic year of 2013/2014 in equation of circle and equation of tangent line of a ...
Mardiyana, M. (Mardiyana)   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Perception of Risk and Terrorism-Related Behavior Change: Dual Influences of Probabilistic Reasoning and Reality Testing

open access: yesFrontiers in Psychology, 2017
The present study assessed the degree to which probabilistic reasoning performance and thinking style influenced perception of risk and self-reported levels of terrorism-related behavior change.
Andrew Denovan   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The Effect of Shape Test in History Subject [PDF]

open access: yes, 2012
The objective of the research is to find out the effect of the formative test form, learning style, and the students' achievement in history by controlling the students' reasoning capacity.
SUYUTI, S. (SUYUTI)
core  

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