Results 91 to 100 of about 1,950,997 (285)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Thinking Style and Fluid Compensation_process

open access: yes, 2020
This project examines how people's thinking style (holistic vs.
Qin Wang, Naomi Mandel, Monika Lisjak
core   +1 more source

Externally oriented thinking style increases primary health care use in adolescence. [PDF]

open access: yesEur J Public Health, 2023
Kekkonen V   +5 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Thinking Style and Fluid Compensation_mediation

open access: yes, 2020
This project examines how people's thinking style (holistic vs.
Qin Wang, Naomi Mandel, Monika Lisjak
core   +1 more source

An empirical study on the relationship between self-efficacy, employees’ creative performance, and thinking style in the Bangladeshi trade companies

open access: yesFuture Business Journal
Purpose This study examines the relationship between self-efficacy, thinking style, and creative performance in Bangladeshi trade companies. Employee creativity is essential for organizational growth in competitive global markets. While self-efficacy has
Md. Mominul Islam, Sabrina Islam
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Interrelations between humor and resource-based thinking as the ground for autocreative processes

open access: yesТеоретическая и экспериментальная психология
Background. The significance of studying resource-based thinking is due to its important role in the organization and successful implementation of various types of activities.
Mergalyas M. Kashapov
doaj   +1 more source

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