Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Psychology, 2019 Background: Metacognitive therapy (MCT) is a modern approach with demonstrated efficacy in current major depressive disorder (MDD). The treatment aims to modify thinking styles of rumination and worry and their underlying metacognitions, which have been ...
Lotta Winter +6 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Model ARIAS berbasis TSTS terhadap Kemampuan Berpikir Kritis Matematis Ditinjau dari Gaya Kognitif
Desimal, 2018 This study aims to determine whether there is the influence of ARIAS model based on Two Stay Two Stray model to critical thinking ability mathematically. This research is Quasi-Experimental Design research.
Desmawati Desmawati, Farida Farida
doaj +1 more source
GAYA BERPIKIR, COPING STRATEGY, DAN RESILIENSI PADA USIA PRODUKTIF [PDF]
, 2016 Penelitian ini bertujuan untuk mengetahui hubungan gaya berpikir dan coping strategy dengan resiliensi pada usia produktif. Metode penelitian yang digunakan adalah metode kuantitatif dengan sampel penelitian berjumlah 234 berusia 25-44 tahun.
Latifah, Ridha Aulia
core
A Traditional English (Not British) Country Gentleman of the Radical Left’: Understanding the Making and Unmaking of Edward Thompson's English Idiom [PDF]
, 2014 This essay discusses E. P. Thompson's relationship with an English sense of tradition, exploring in particular his shifting characterisation of an English idiom in the three closely linked, polemical rejoinders he offered to the ideas advanced by major ...
KENNY, MH
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
ANALISIS KEMAMPUAN COMPUTATIONAL THINKING SISWA DALAM MENYELESAIKAN SOAL HOTS OPEN ENDED DITINJAU DARI GAYA KOGNITIF REFLEKTIF DAN IMPULSIF [PDF]
The ability of computational thinking is the ability needed to balance the development in the 21st century digitalization era. The purpose of this study was to describe the ability of students' computational thinking in solving open ended HOTS problems ...
Amanah, Nabilla Nur
core
An empirical study to investigate the effects of thinking styles on emotional intelligence: A case study of Jihad Agriculture Organization of east Azerbaijan province [PDF]
, 2013 An empirical study to investigate the effects of thinking styles on emotional intelligence among employees of agriculture industry in east Azerbaijan province.
Habibeh Ayagh, Hassan Darvish
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source