Investigation of Thiocarbamates as Potential Inhibitors of the SARS-CoV-2 Mpro
Pharmaceuticals, 2021 In the present study we tested, using the microscale thermophoresis technique, a small library of thionocarbamates, thiolocarbamates, sulfide and disulfide as potential lead compounds for SARS-CoV-2 Mpro drug design. The successfully identified binder is
Jakub Nowak +2 more
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Synthetic Routes to, Stabilities and Transformations of, and Characterization of (Carbamoyl)disulfanyl Chlorides and Related Compounds1,2 [PDF]
MoleculesPreviously unobserved (carbamoyl)disulfanyl chlorides were prepared by (i) addition of limiting aromatic secondary amine to (chlorocarbonyl)disulfanyl chloride; (ii) Harris reactions of sulfur dichloride with appropriate O-alkyl N-methyl-N ...
Phillip T. Goldblatt +9 more
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Network pharmacology refined with non-ubiquity and decoy-controlled molecular docking reveals insights into Moringa oleifera phytochemicals targeting insulin resistance [PDF]
Frontiers in BioinformaticsMoringa oleifera phytochemicals were predicted to target insulin resistance proteins using a modified network pharmacology and molecular docking approach. Two hundred ninety M.
Armi Katrina Santos-Enriquez +4 more
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New method for synthesis of N-alkyl and N,N-dialkyl-O-ethyl and O-isopropylthiocarbamates by oxidation of ammonium salt of xhantogenic acid [PDF]
Hemijska Industrija, 2010 A synthesis of N-alkyl and N,N-dialkyl-O-ethyl and O-isopropyl thiocarbamates by oxidation of ammonium salt of ethyl and isopropylxanthogenic acid in a presence of sodium hypochlorite and hydrogen peroxide were performed.
Milisavljević Smiljka S. +2 more
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Enantiopure (S)-butan-2-yl N-(4-x-phenyl)thiocarbamates, x = NO2, OCH3, F, and Cl
Acta Crystallographica Section E: Crystallographic Communications, 2023 The structures of (S)-butan-2-yl N-(4-nitrophenyl)thiocarbamate, C11H14N2O3S, (I), (S)-butan-2-yl N-(4-methoxyphenyl)thiocarbamate, C12H17NO2S, (II), (S)-butan-2-yl N-(4-fluorophenyl)thiocarbamate, C11H14FNOS, (III), and (S)-butan-2-yl N-(4-chlorophenyl ...
Werner Kaminsky, Max Kaganyuk
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Groups of antifungal drugs with role in animal health - Synthesis [PDF]
Medicamentul Veterinar, 2021 Fungal infections are an important part of infectious pathology, their incidence increasing considerably, as a result of the widespread use of antibiotics, corticosteroids, cytostatics and immunosuppressive drugs.
Răzvan F. Moruzi +6 more
doaj
Cytotoxic Thiocarbamate Derivatives of Boldine [PDF]
Natural Product Communications, 2010 Two new boldine derivatives: the 3-thiocarbamateboldine (3) and the 2,9 -O,O-diacetyl-3-thiocarbamateboldine (4) have been synthesized and their cytotoxicity evaluated.
Franz A, Thomet +4 more
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Journal of the Turkish Chemical Society, Section A: Chemistry, 2020 The phytochemical composition of medicinal plants is responsible for the ethnopharmacological applications. These phytochemicals vary in plants of same species planted in various geographical locations.
Atolani ATOLANI +5 more
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Zeitschrift für Naturforschung B, 1955 Rhodanide und konz. Schwefelsäure reagieren unter Bildung von Estern miteinander, deren Hydrolyse zu Monothiocarbamidsäure-S-R-estern (Thiocarbamaten) führt.
R. Riemschneider, O. Lorenz
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Thiocarbamates as plant growth regulators [PDF]
Plant Physiology, 1961 The findings of van der Kerk and his coworkers (10) that carboxymethyl (limietlhyldithiocarbamate (1) caused epinastic curvature ancl leaf deformations as well as some elongation of Avena coleoptile tissue related its action as a growth regulator to that of indole-3-acetic acid and other aromatic structures.
R M, Muir, C, Hansch, J, Gally
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