Results 161 to 170 of about 182,890 (341)

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud   +12 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

The effect ofquetiapine on the invitro serum concentration of free thiols and thiobarbituric acid-reacting substances

open access: yesPsychiatria i Psychologia Kliniczna, 2013
Quetiapine, a second generation antipsychotic, has no significant effect on the occurrence of tardive dyskinesia or other motoric disorders whose aetiology may be related to a pro- and antioxidative imbalance.
Anna Dietrich-Muszalska   +4 more
doaj  

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Tailored Stereo‐Configuration of Crosslinkable Polyester‐Based Solid Polymer Electrolytes for All‐Solid‐State and Binder‐Free Li Metal Batteries

open access: yesAdvanced Science, EarlyView.
Variations in polymer conformations of unsaturated poly(n‐alkyl esters) driven by monomer‐level stereochemistry directly govern Li+ solvation structures in polymer host matrices. The synergistic strategies of polymer conformation control, UV‐induced interchain crosslinking, and end‐group fluorination are implemented for engineering advanced solid ...
Hyun Jun Song   +11 more
wiley   +1 more source

Polysiloxane‐Based Single‐Ion Conducting Polymer Electrolyte for Sodium Batteries

open access: yesAdvanced Science, EarlyView.
We report a polysiloxane‐based single‐ion conducting polymer electrolyte for sodium batteries. This polymer electrolyte exhibits high Na+ ion mobility and a wide electrochemical stability window, enabling the long‐term stable cycling of various cathode chemistries – also at room temperature, elevated dis‐/charge rates and active material mass loadings,
Yixuan Guo   +7 more
wiley   +1 more source

Revealing the Ion Regulation Effect of Zwitterionic All‐Solid‐State Electrolytes in Lithium Metal Batteries

open access: yesAdvanced Science, EarlyView.
This study investigates zwitterionic all‐solid‐state electrolytes, demonstrating strong carboxyl‐Li+ interaction that forms “ion‐enrichment pathway”‐like domains and manipulates Li+ deposition. Additionally, surface‐enriched zwitterions generate a dual‐layer SEI with an inner Li2O‐rich and outer LiF‐rich structure. Through ionic flux regulation and SEI
Wentao Xie   +13 more
wiley   +1 more source

Oxidative Stress and NRF2-Mediated Redox Regulation in Incomplete Systemic Lupus Erythematosus and Systemic Lupus Erythematosus. [PDF]

open access: yesAntioxidants (Basel)
Liu L   +6 more
europepmc   +1 more source

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

open access: yesAdvanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng   +11 more
wiley   +1 more source

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