Results 101 to 110 of about 1,367 (120)

Interactions of type II topoisomerases with divalent metal ions and therapeutic drugs [PDF]

Pitts, Steven Lee
core  

Thionucleotides as Inhibitors of Ribonucleotide Reductase

Nucleosides, Nucleotides and Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
B, Roy, S, Chambert, M, Lepoivre, J L, Décout   +3 more
  +5 more sources

The enzymatic hydrolysis of the phosphate ester bond in some thionucleotides

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1979
We prepared the 5'- and 3'-O-phosphorothioate esters of the antitumor agent O2 : 2'-anhydro-1-beta-D-arabinosylcytosine. We also included in this study esters of 2'-thio-2'-deoxycytidine, namely, 2'-S-dCyd-2' : 3'-P, 2'-S-dCyd-2'-P, and 2'-S-dCyd-3'-P, along with natural nucleotides.
C C, Lee, W H, Schrier, J, Nagyvary
openaire   +3 more sources

Optical rotatory dispersion and circular dichroism of sulfur-containing nucleosides and nucleotide and of the ribonuclease-thionucleotide complex

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
Abstract Optical rotatory dispersion (ORD) and circular dichroism (CD) of sulfur-containing nucleosides (4-thiouridine, 6-thioguanosine and 6-thioinosine) and a nucleotide (4-thiouridine 2′(3′)-monophosphate) as well as a complex between ribonuclease (EC 2.7.7.16) and the nucleotide were measured in the near-ultraviolet and ultraviolet regions.
T, Samejima, M, Kita, M, Saneyoshi, F, Sawada   +3 more
openaire   +3 more sources

Mono- and Binuclear Copper(I) Complexes of Thionucleotide Analogues and Their Catalytic Activity on the Synthesis of Dihydrofurans

Inorganic Chemistry, 2014
The reaction of copper(I) halides with 2-thiouracil (TUC), 6-methyl-2-thiouacil (MTUC), and 4-methyl-2-mercaptopyrimidine (MPMTH) in the presence of triphenylphosphine (tpp) in a 1:1:2 molar ratio results in a mixed-ligand copper(I) complex with the formulas [Cu2(tpp)4(TUC)Cl] (1), [Cu2(tpp)4(MTUC)Cl] (2), [Cu(tpp)2(MPMTH)Cl]·(1)/2CH3OH (3), [Cu(tpp)2 ...
D C, Charalampou, N, Kourkoumelis, S, Karanestora, L P, Hadjiarapoglou, V, Dokorou, S, Skoulika, A, Owczarzak, M, Kubicki, S K, Hadjikakou   +8 more
openaire   +3 more sources

Activation of 5-lipoxygenase by guanosine 5′-O-(3-thiotriphosphate) and other nucleoside phosphorothioates: Redox properties of thionucleotide analogs

Archives of Biochemistry and Biophysics, 1989
The stable nucleotide analog guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) was found to be a very potent activator of 5-lipoxygenase in cell-free preparations from rat polymorphonuclear (PMN) leukocytes, causing a 10-fold stimulation of arachidonic acid oxidation at concentrations as low as 0.5-1 microM.
D, Denis, L Y, Choo, D, Riendeau
openaire   +3 more sources

Possible new routes to 3′-thionucleotides and their polymers of pharmacological and prebiotic interest

Structural Chemistry, 2023
Joseph Nagyváry
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Thionucleotides in the transfer ribonucleic acid of

Life Sciences, 1972
B. Thimmappaya, Joseph D. Cherayil
openaire   +2 more sources

Thionucleotides in transfer ribonucleic acid. Addition of N-ethylmaleimide and formation of mixed disulfides with thiol compounds

Biochemistry, 1968
John. Carbon, Harold. David
openaire   +2 more sources

Stability constants of magnesium and cadmium complexes of adenine nucleotides and thionucleotides and rate constants for formation and dissociation of magnesium-ATP and magnesium-ADP

Biochemistry, 1984
Vincent L. Pecoraro, Jeffrey D. Hermes, W. W. Cleland   +2 more
openaire   +2 more sources