Results 111 to 120 of about 1,432 (144)

A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa. [PDF]

Nat Commun
Zhan X, Zhang K, Wang C, Fan Q, Tang X, Zhang X, Wang K, Fu Y, Liang H.   +8 more
europepmc   +1 more source

N-acetyl cysteine turns EPAC activators into potent killers of acute lymphoblastic leukemia cells. [PDF]

J Biol Chem
Richartz N, Pietka W, Yadav A, Bostad M, Bhagwat S, Naderi S, Naderi EH, Stokke T, Ruud E, Blomhoff HK.   +9 more
europepmc   +1 more source

Interactions of type II topoisomerases with divalent metal ions and therapeutic drugs [PDF]

Pitts, Steven Lee
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Thionucleotides as Inhibitors of Ribonucleotide Reductase

Nucleosides, Nucleotides and Nucleic Acids, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
B, Roy, S, Chambert, M, Lepoivre, J L, Décout   +3 more
openaire   +3 more sources

The enzymatic hydrolysis of the phosphate ester bond in some thionucleotides

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1979
We prepared the 5'- and 3'-O-phosphorothioate esters of the antitumor agent O2 : 2'-anhydro-1-beta-D-arabinosylcytosine. We also included in this study esters of 2'-thio-2'-deoxycytidine, namely, 2'-S-dCyd-2' : 3'-P, 2'-S-dCyd-2'-P, and 2'-S-dCyd-3'-P, along with natural nucleotides.
C C, Lee, W H, Schrier, J, Nagyvary
openaire   +3 more sources

Impact of Mercaptopurine Metabolites on Disease Outcome in the AIEOP‐BFM ALL 2009 Protocol for Acute Lymphoblastic Leukemia [PDF]

Clinical pharmacology and therapy, 2023
In the maintenance phase of Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP)‐ Berlin‐Frankfurt‐Muenster (BFM) acute lymphoblastic leukemia (ALL) 2009 protocol, mercaptopurine (MP) is given at the planned dose of 50 mg/m2/day; however ...
R. Franca, G. Stocco, V. Kiren, Antimo Tessitore, F. Fagioli, P. Quarello, N. Bertorello, C. Rizzari, A. Colombini, L. Bettini, F. Locatelli, L. Vinti, Katia Girardi, D. Silvestri, M. Valsecchi, G. Decorti, M. Rabusin   +16 more
semanticscholar   +3 more sources

Mono- and Binuclear Copper(I) Complexes of Thionucleotide Analogues and Their Catalytic Activity on the Synthesis of Dihydrofurans

Inorganic Chemistry, 2014
The reaction of copper(I) halides with 2-thiouracil (TUC), 6-methyl-2-thiouacil (MTUC), and 4-methyl-2-mercaptopyrimidine (MPMTH) in the presence of triphenylphosphine (tpp) in a 1:1:2 molar ratio results in a mixed-ligand copper(I) complex with the formulas [Cu2(tpp)4(TUC)Cl] (1), [Cu2(tpp)4(MTUC)Cl] (2), [Cu(tpp)2(MPMTH)Cl]·(1)/2CH3OH (3), [Cu(tpp)2 ...
D C, Charalampou, N, Kourkoumelis, S, Karanestora, L P, Hadjiarapoglou, V, Dokorou, S, Skoulika, A, Owczarzak, M, Kubicki, S K, Hadjikakou   +8 more
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Possible new routes to 3′-thionucleotides and their polymers of pharmacological and prebiotic interest

Structural Chemistry, 2023
J. Nagyvary
openaire   +2 more sources

Optical rotatory dispersion and circular dichroism of sulfur-containing nucleosides and nucleotide and of the ribonuclease-thionucleotide complex

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
Abstract Optical rotatory dispersion (ORD) and circular dichroism (CD) of sulfur-containing nucleosides (4-thiouridine, 6-thioguanosine and 6-thioinosine) and a nucleotide (4-thiouridine 2′(3′)-monophosphate) as well as a complex between ribonuclease (EC 2.7.7.16) and the nucleotide were measured in the near-ultraviolet and ultraviolet regions.
T, Samejima, M, Kita, M, Saneyoshi, F, Sawada   +3 more
openaire   +3 more sources