Results 11 to 20 of about 1,299 (83)
Insights into the cellular pharmacokinetics and pharmacodynamics of thiopurine antimetabolites in a model of human intestinal cells [PDF]
, 2021 Thiopurines, immunomodulating drugs used in the management of different chronic autoimmune conditions and as anti-leukemic agents, may exert in some cases gastrointestinal toxicity.
Di Paolo V. +6 more
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Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA [PDF]
, 2016 UVA accounts for about 95% of the solar ultraviolet (UV) radiation that reaches Earth and most likely contributes to human skin cancer risk. In contrast to UVB, which comprises the remaining 5% and is absorbed by DNA nucleobases to cause direct ...
Karran, Peter, Guven, Melisa, Brem, Reto
core +1 more source
Exploring ribozymes, riboswitches and RNA modifications
, 2018 Ribonukleinsäuren (RNA) haben verschiedene Elemente mit denen sie die Regulation von Genen steuern können. Während einige durch Konformationsänderungen aktiv werden, wie zum Beispiel Ribozyme und Riboschalter, stützen sich andere RNAs auf Modifikationen ...
Gasser, Catherina
core +3 more sources
The nucleotide binding domains of multidrug resistance-p-glycoproteins [PDF]
, 2001 Bibliography: leaves 116 ...
De Wet, Heidi
core +1 more source
, 2014 6-mercaptopurine (6-MP) is a purine antimetabolite and prodrug that undergoes extensive intracellular metabolism to produce thionucleotides, active metabolites which have cytotoxic and immunosuppressive properties.
Aarons, Leon; id_orcid +1 more
core +1 more source
Studies of some thionucleotides of prebiotic interests
, 1978 Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the ...
Chou, Christie Shu-Tung
core +1 more source
Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
, 2020 UVA accounts for about 95% of the solar ultraviolet (UV) radiation that reaches Earth and most likely contributes to human skin cancer risk. In contrast to UVB, which comprises the remaining 5% and is absorbed by DNA nucleobases to cause direct ...
Reto Brem (8017) +2 more
core
, 1997 Reactions of trans-dicyanodichloroaurate(III) trans-dibromodicyanoaurate(III), trans-diamminedichlorogold(III), cis-diammine(aqua)chloroplatinum(II), cis-ammineaqua-(cyclohexylamine)chloroplatinum(II), chloro(terpyridine)platinum(II) and chloro ...
Ericson, Anna
core +1 more source
, 1995 Previous studies demonstrated that the thrombin-induced permeability of endothelial cell monolayers is reduced by the elevation of cGMP. In the present study, the presence of cGMP-dependent protein kinase (cGMP-PK) immunoreactivity and activity in ...
Vaandrager, A.B. +5 more
core
Evidence for a PI3-kinase independent pathway in the regulation of Rap1b activation downstream of the P2Y12 receptor in platelets. [PDF]
Platelets, 2022 Dangelmaier C, Kunapuli SP.
europepmc +1 more source