Results 1 to 10 of about 38,014 (298)

Thiophene derivatives activity against the protozoan parasite Leishmania infantum [PDF]

International Journal for Parasitology: Drugs and Drug Resistance, 2023
Treatments against leishmaniasis are limited and the development of new molecules is crucial. One class of developmental drug that has shown activity against the parasite Leishmania are thiophene derivatives.
Sophia Bigot, Philippe Leprohon, Abimael Vasquez, Rohit Bhadoria, Rachid Skouta, Marc Ouellette   +5 more
doaj   +2 more sources

New thiophene derivatives: chemoselective synthesis, antitumor effectiveness, structural characterization, DFT calculations, Hirshfeld surface, and Fukui function analysis [PDF]

BMC Chemistry
In this study, the chemoselective synthesis of two new thiophene derivatives is presented. The structure of newly synthesized thiophenes derivatives; ethyl 4-acetyl-3-phenyl-5-(phenylamino)thiophene-2-carboxylate (5) and ethyl (E)-4-(3-(dimethylamino ...
Abdullatif Bin Muhsinah, Mohammed M. Alharbi, Nabila A. Kheder, Saied M. Soliman, Hazem A. Ghabbour, Naglaa S. Mahmoud, Ismail A. Elhaty, Yahia N. Mabkhot   +7 more
doaj   +2 more sources

Anticorrosive Effects of Some Thiophene Derivatives Against the Corrosion of Iron: A Computational Study [PDF]

Frontiers in Chemistry, 2018
It is known that iron is one of the most widely used metals in industrial production. In this work, the inhibition performances of three thiophene derivatives on the corrosion of iron were investigated in the light of several theoretical approaches.
Lei Guo, Zaki S. Safi, Savas Kaya, Wei Shi, Burak Tüzün, Nail Altunay, Cemal Kaya   +6 more
doaj   +2 more sources

Synthesis of aryl-substituted thieno[3,2-b]thiophene derivatives and their use for N,S-heterotetracene construction [PDF]

Beilstein Journal of Organic Chemistry, 2019
Fiesselmann thiophene synthesis was applied for the convenient construction of thieno[3,2-b]thiophene derivatives. Thus, new 5- or 6-aryl-3-hydroxythieno[3,2-b]thiophene-2-carboxylates were obtained by condensation of 5- or 4-aryl-3-chlorothiophene-2 ...
Nadezhda S. Demina, Nikita A. Kazin, Nikolay A. Rasputin, Roman A. Irgashev, Gennady L. Rusinov   +4 more
doaj   +2 more sources

Supramolecular Thiophene-Based Materials: A Few Examples of the Interplay between Synthesis, Optoelectronic Properties and Applications

Organic Materials, 2021
Supramolecular nanostructured thiophene based materials with optoelectronic functions are of wide current interest and are playing a crucial role in different fields of nanoscience and nanotechnology.
Francesca Di Maria, Mattia Zangoli, Giovanna Barbarella   +2 more
doaj   +1 more source

Synthesis and analgesic activity evaluation of derivatives of 2-[(1,4-dioxo-1-amino-4-arylbutyl-2-en-2-yl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

Chimica Techno Acta, 2021
The synthesis of new derivatives of 2-[(1,4-dioxo-1-amino-4-arylbutyl-2-en-2-yl)amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid is described.
Alena I. Siutkina, Ramiz R. Makhmudov, Daria A. Shipilovskikh   +2 more
doaj   +1 more source

Synthesis of Thiophene-Based Flavone Schiff Base Derivatives and a Comparison of Biological Activities with Furanflavone Analogs [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2022
In this investigation, a series of thiophene-based flavone Schiff base derivatives were synthesized starting from phloroglucinol. Initially, the acetophenone derivative of phloroglucinol, 2-hydroxy-4,6-di-O-methyl phloroglucinol (3) was prepared by ...
Hari Babu Bollikolla, Bala Murali krishna khandapu, Jagan Mohana Rao Saketi, Rambabu Anandam, Anitha Uppalapati   +4 more
doaj   +1 more source

Synthesis, DFT investigations, antioxidant, antibacterial activity and SAR-study of novel thiophene-2-carboxamide derivatives

BMC Chemistry, 2023
Synthetic strategy for the synthesis of thiophene 2-carboxamide derivatives substituted with hydroxyl, methyl and amino groups at position-3 was proposed.
Heba M. Metwally, Norhan A. Khalaf, Ehab Abdel-Latif, Mohamed A. Ismail   +3 more
doaj   +1 more source

Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors

Plants, 2022
Naturally, thiophenes represent a small family of natural metabolites featured by one to five thiophene rings. Numerous plant species belonging to the family Asteraceae commonly produce thiophenes.
Sabrin R. M. Ibrahim, Abdelsattar M. Omar, Alaa A. Bagalagel, Reem M. Diri, Ahmad O. Noor, Diena M. Almasri, Shaimaa G. A. Mohamed, Gamal A. Mohamed   +7 more
doaj   +1 more source

Thiophene-Based Covalent Organic Frameworks: Synthesis, Photophysics and Light-Driven Applications

Molecules, 2021
Porous crystalline materials, such as covalent organic frameworks (COFs), have emerged as some of the most important materials over the last two decades due to their excellent physicochemical properties such as their large surface area and permanent ...
Rubén Caballero, Boiko Cohen, Mario Gutiérrez   +2 more
doaj   +1 more source