Results 181 to 190 of about 14,349 (246)

Design, synthesis, <i>in vitro</i>, and <i>in silico</i> studies on promising α-glucosidase inhibitors based on a quinazolinone-thiophene scaffold. [PDF]

RSC Adv
Baghershahi P, Dastyafteh N, Halimi M, Mohammadi-Khanaposhtani M, Ghafouri SN, Noori M, Ghasemi F, Mojtabavi S, Faramarzi MA, Torabi M, Alikhani M, Larijani B, Javanshir S, Mahdavi M.   +13 more
europepmc   +1 more source

Single crystal X-ray-structurally characterized Mo(vi) complexes of thiophene-appended amide-imine conjugates for optical recognition of calcon and 2-aminobutyric acid. [PDF]

RSC Adv
Maji S, Mandal P, De AK, Chatterjee S, Das D.   +4 more
europepmc   +1 more source

Design, synthesis, characterization, pharmacological evaluation and in silico ADMET and molecular docking and dynamics simulations of a novel series of N-substituted pyrazole from chalcone derivatives. [PDF]

Sci Rep
Hafez HN, Otaif HY, Alshammari BH, Alhebshe NS, El-Sayed AF, Abbas HS, Ammar RA.   +6 more
europepmc   +1 more source

Development of new pyrazole-thiophene hybrids: synthesis, anticancer assessment, and molecular docking insights. [PDF]

RSC Adv
Samy S, Mahmoud SE, Abdel-Galil E, Abdel-Latif E, Said GE.   +4 more
europepmc   +1 more source

Discovery of tunable and soluble organic emitters for solid-state lasers with a self-driving laboratory. [PDF]

Nat Commun
Park HS, Mazaheri M, Choi C, Hao H, Avagliano D, Isbrandt E, S B Karunathilaka B, Adachi C, Aspuru-Guzik A.   +8 more
europepmc   +1 more source

Discovery of VU6053371/BI03738809: A First-in-Class Selective and CNS-Penetrant mGlu₃ Positive Allosteric Modulator (PAM) with Efficacy in a Preclinical Cognition Model. [PDF]

ACS Chem Neurosci
Jones CA, Duncan RA, Gilliland KM, Reed CW, Haymer DH, Spearing PK, Capstick RA, Roland BP, Vinson P, Quitalig M, Baggeroer C, Billard NB, Dickerson JW, Xiang Z, Kramlinger VM, Boutaud O, Schlichtiger J, Jones CK, Niswender CM, Cho HP, Rook JL, Wotjak CT, Freiwald M, Giovannini R, Sommer H, Hobson S, Conn PJ, Melancon BJ, Lindsley CW.   +28 more
europepmc   +1 more source

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Plasma Polymerization of Thiophene Derivatives

Langmuir, 2003
To obtain plasma polymerized (PP) layers with a high retention of the conjugated monomer structure, fragmentation during deposition should be minimized. Different methylated and halogenated thiophenes were used as monomers in plasma polymerization, and the influence of the substituent(s) on fragmentation during deposition was investigated. With the use
Groenewoud, L.M.H., Engbers, G.H.M., Feijen, Jan   +2 more
openaire   +3 more sources

Reaction of Dicarbomethoxycarbene with Thiophene Derivatives

The Journal of Organic Chemistry, 2009
Photolysis of derivatives of dimethylmalonate thiophene-S,C-ylide provides dicarbomethoxycarbene, which can react with thiophene to form dimethyl (2-thienyl)malonate. By generation of dicarbomethoxycarbene from the dibenzothiophene-based ylide in neat thiophene, it is shown that the thienylmalonate is not a product of rearrangement of the thiophene ...
Jenks, William, Heying, Melanie, Stoffregen, Stacey, Rockafellow, Erin   +3 more
openaire   +3 more sources

Synthesis of 2-Thiophene Derivatives

Journal of Pharmaceutical Sciences, 1962
The objective of this present study is the synthesis of certain new 2-thiophene derivatives to be evaluated as potential antispasmodic, analgesic, or local anesthetic agents. The first part of this study concerns the synthesis of β-aminoketones (Mannich bases).
F C, ROGERS, W L, NOBLES
openaire   +2 more sources

Functional derivatives of thiophene

Chemistry of Heterocyclic Compounds, 1973
A method was developed for the synthesis of 5-acylamino-2,3dimethyl- and 5-acylamino2,3-tetramethyle nethiophenes by decarboxylation of the corresponding 5-acylaminothiop hene4-carboxylie acids. The azo coupling and arninomethylatio n of the synthesized acylaminothiophenes were studied.
V. I. Shvedov, I. A. Kharizomenova, A. N. Grinev   +2 more
  +4 more sources