Results 271 to 280 of about 31,059 (323)

Thioredoxins and thioredoxin reductase in chloroplasts: A review

Gene, 2019
The chloroplastic thioredoxins (Trxs), a family of thiol-disulphide oxidoreductases, are reduced by either ferredoxin (Fd)-dependent Trx reductase (FTR) or reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent Trx reductase (NTR). Two Trx systems are present in chloroplasts including Trxs, Trx-like proteins, and reductase FTR and NTRC ...
Zhenhui Kang, Zhiping Zhao
exaly   +4 more sources

Thioredoxins in chloroplasts

Current Genetics, 2007
Thioredoxins (TRXs) are small disulfide oxidoreductases of ca. 12 kDa found in all free living organisms. In plants, two chloroplastic TRXs, named TRX f and TRX m, were originally identified as light dependent regulators of several carbon metabolism enzymes including Calvin cycle enzymes.
Stéphane D Lemaire, Mirko Zaffagnini, Vincent Massot   +2 more
exaly   +4 more sources

Thioredoxin Superfamily and Thioredoxin‐Inducing Agents

Annals of the New York Academy of Sciences, 2002
Abstract: Mammalian thioredoxin (TRX) with redox‐active dithiol in the active site plays multiple roles in intracellular signaling and resistance against oxidative stress. TRX is induced by a variety of stresses including infectious agents as well as hormones and chemicals.
Kiichi, Hirota, Hajime, Nakamura, Hiroshi, Masutani, Junji, Yodoi   +3 more
openaire   +2 more sources

Measurement of Thioredoxin and Thioredoxin Reductase

Current Protocols in Toxicology, 2005
AbstractThe thioredoxin system is ubiquitous, providing reducing equivalents to essential biosynthetic enzymes like ribonucleotide reductase. It is essential for cellular redox regulation, control of oxidative stress, and protection against oxidative damage.
E S, Arnér, A, Holmgren
openaire   +2 more sources

Seed thioredoxin h

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2016
Thioredoxins are nearly ubiquitous disulfide reductases involved in a wide range of biochemical pathways in various biological systems, and also implicated in numerous biotechnological applications. Plants uniquely synthesize an array of thioredoxins targeted to different cell compartments, for example chloroplastic f- and m-type thioredoxins involved ...
Per Hägglund, Christine Finnie, Hiroyuki Yano, Azar Shahpiri, Bob B. Buchanan, Anette Henriksen, Birte Svensson   +6 more
openaire   +3 more sources

Kinetics of electron transfer from thioredoxin reductase to thioredoxin

Biochemistry, 1991
The reduction of Escherichia coli thioredoxin by thioredoxin reductase was studied by stopped-flow spectrophotometry. The reaction showed no dependence on thioredoxin concentration, indicating that complex formation was rapid and occurred during the dead time of the instrument.
J A, Navarro, F K, Gleason, M A, Cusanovich, J A, Fuchs, T E, Meyer, G, Tollin   +5 more
openaire   +2 more sources

Cytosolic, Mitochondrial Thioredoxins and Thioredoxin Reductases in Arabidopsis Thaliana

Photosynthesis Research, 2004
Thioredoxins, by reducing disulfide bridges are one of the main participants that regulate cellular redox balance. In plants, the thioredoxin system is particularly complex. The most well-known thioredoxins are the chloroplastic ones, that participate in the regulation of enzymatic activities during the transition between light and dark phases.
Bréhélin, Claire, Laloi, Christophe, Setterdahl, Aaron, Knaff, David, Meyer, Yves   +4 more
openaire   +3 more sources

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

Biochemistry, 1982
A reproducible scheme has been developed for the preparation of rat liver thioredoxin and thioredoxin reductase (EC 1.6.4.5) by using assays based on reduction of insulin and 5,5'-dithiobis(2-nitrobenzoic acid), respectively. Both proteins were purified to homogeneity, as judged from polyacrylamide gel electrophoresis.
M, Luthman, A, Holmgren
openaire   +2 more sources

Thioredoxin and NADP-thioredoxin reductase from cultured carrot cells

Planta, 1987
Dark-grown carrot (Daucus carota L.) tissue cultures were found to contain both protein components of the NADP/thioredoxin system--NADP-thioredoxin reductase and the thioredoxin characteristic of heterotrophic systems, thioredoxin h. Thioredoxin h was purified to apparent homogeneity and, like typical bacterial counterparts, was a 12-kdalton (kDa ...
T C, Johnson, R Q, Cao, J E, Kung, B B, Buchanan   +3 more
openaire   +3 more sources

Studies toward Novel Peptidomimetic Inhibitors of Thioredoxin–Thioredoxin Reductase System

Journal of Medicinal Chemistry, 2011
Thioredoxins (Trx) are ubiquitous multifunctional low-molecular weight proteins that together with thioredoxin reductases (TrxR) participate in the maintenance of protein thiol homeostasis in NADPH-dependent reactions. An increasing number of data reveal that the Trx-TrxR system is an attractive target for anticancer therapies.
Szymon, Kłossowski, Angelika, Muchowicz, Małgorzata, Firczuk, Marta, Swiech, Adam, Redzej, Jakub, Golab, Ryszard, Ostaszewski   +6 more
openaire   +2 more sources