Editorial: Drug repurposing for cancer treatment: current and future directions. [PDF]
Lampros M +4 more
europepmc +1 more source
Cryptotanshinone inhibits <i>Staphylococcus aureus</i> NdhC via uncompetitive inhibition: Collateral sensitivity in respiratory-deficient SCVs. [PDF]
Xue ZJ +8 more
europepmc +1 more source
Acute hypothermia induced by valproic acid. [PDF]
Dasara H, Conn B, Shamim S.
europepmc +1 more source
Synergistic anticancer and antibacterial effects of novel regimens of phytopolyphenols and repurposing drugs on cultured cells. [PDF]
Yeh YL, Wang YJ, Lin-Shiau SY.
europepmc +1 more source
Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis [PDF]
The neuroleptic drug thioridazine has been recently repositioned as possible antitubercular drug. Thioridazine showed antitubercular activity against drug resistant mycobacteria but it is endowed with adverse side effects. A small library of thioridazine
Camila M Ribeiro +2 more
exaly +8 more sources
Thioridazine: a selective inhibitor of peroxisomal β-oxidation in vivo [PDF]
In vivo administration of the phenothiazine drug, thioridazine, inhibits hepatic peroxisomal β-oxidation in mice. In starving animals, 3-hydroxybutyrate concentration is not decreased by thioridazine treatment.
Christiane van den Branden +2 more
exaly +2 more sources
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Concentrations of thioridazine and thioridazine metabolites in erythrocytes
Psychopharmacology, 1986The concentrations of thioridazine and its main metabolites in erythrocytes from 61 thioridazine-treated patients were determined by gas-liquid chromatography. The mean and range of the erythrocyte concentrations, expressed as percentage of the corresponding plasma concentrations, were: thioridazine, 5.1% (2.0-10.6); side-chain sulfoxide, 5.6% (1.6-10 ...
C, Svensson +3 more
openaire +2 more sources
Artifacts in the analysis of thioridazine and other neuroleptics
Although the sensitivity to light of thioridazine and its metabolites has been described, the problem does not seem to be widely acknowledged. Indeed, a survey of the literature shows that assays of these compounds under light-protected conditions have ...
Clara Benzi Schmid, Pierre Baumann
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