NRF2 signalling in cytoprotection and metabolism
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami+4 more
wiley +1 more source
Supersulfide biology and translational medicine for disease control
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu+5 more
wiley +1 more source
Physiological function and catalytic versatility of bacterial multihaem cytochromescinvolved in nitrogen and sulfur cycling [PDF]
Bacterial MCCs (multihaem cytochromes c) represent widespread respiratory electron-transfer proteins. In addition, some of them convert substrates such as nitrite, hydroxylamine, nitric oxide, hydrazine, sulfite, thiosulfate or hydrogen peroxide. In many
Arslan+54 more
core +1 more source
Proteomics of Carbon Fixation Energy Sources in Halothiobacillus neapolitanus [PDF]
Through the use of proteomics, it was uncovered that the autotrophic, aerobic purple sulfur bacterium Halothiobacillus neapolitanus displays changes in cellular levels of portions of its carbon dioxide uptake and fixation mechanisms upon switch from ...
Hilliard, Newton P, Jr.+3 more
core +3 more sources
Deletion of flavoredoxin gene in Desulfovibrio gigas reveals its participation in thiosulfate reduction [PDF]
: The gene encoding Desulfovibrio gigas flavoredoxin was deleted to elucidate its physiological role in the sulfate metabolism. Disruption of flr gene strongly inhibited the reduction of thiosulfate and exhibited a reduced growth in the presence of ...
Broco, Manuela+3 more
core +2 more sources
The chemistry of thiosulfate and vascular calcification [PDF]
Thiosulfate has been shown to inhibit vascular calcification in uremic rats and may inhibit calcification in humans with end-stage renal disease but whether this is due to a systemic or local action is unknown. The underlying mechanism is also unclear but complexation of calcium ions has been proposed.In vitro assays were used to determine the effect ...
W. Charles O'Neill+1 more
openaire +3 more sources
Electrochemistry and Spectroscopy of Sulfate and Thiosulfate Complexes of Iron Porphyrins [PDF]
The electrochemical and spectroscopic properties of the complex formed by the addition of thiosulfate to ferric porphyrins were examined. The NMR spectrum of the thiosulfate–ferric porphyrin complex was consistent with a high-spin ferric complex, while ...
Crawford, Philip Walter+1 more
core +1 more source
Tetrathionate production by sulfur-oxidizing bacteria and the role of tetrathionate in the sulfur cycle in sediments of the Baltic Sea [PDF]
The role of tetrathionate in the sulfur cycle of Baltic Sea sediments was investigated in different habitats and under a variety of environmental conditions.
Imhoff, Johannes F., Podgorsek, L.
core +1 more source
Protonic ceramic fuel cells offer a promising route to generate power efficiently but face critical challenges in achieving industrially viable activity and stability at their cathodes in CO2‐containing air. This report proposes a new cathode material design strategy to enable the cathode to be both catalytically active and CO2 tolerant through the ...
Desheng Feng+14 more
wiley +1 more source
Catalytic Reduction of Bisulfite by Myoglobin/Surfactant Films [PDF]
The voltammetry of bisulfite at a film formed with myoglobin was studied in aqueous solutions. A broad wave was observed for the reduction of bisulfite.
Abdellatty, Radalla+2 more
core +1 more source