ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Continuous sampling of cerebrospinal fluid from the third ventricle of the hypothalamus to identify accumulating or depleting metabolites during hibernation. [PDF]
Markussen FAF +4 more
europepmc +1 more source
Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu +4 more
wiley +1 more source
Description of an Intraoral Lingual Arch Fixation Technique for the Treatment of Mandibular Body Fractures in Dogs and Its Application in Six Patients. [PDF]
San Román-Llorens F +5 more
europepmc +1 more source
Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea +53 more
wiley +1 more source
Radix, Matrix : the third body in Levinas's ethics
Autor próbuje określić zręby dyskursu zdolnego przezwyciężyć paradoksalną neutralizację, której w myśli Levinasa ulega Inny; stara się pokazać, że aby uchronić relację pomiędzy mną a Innym przed generalizacją abstrakcji, musimy przestać operować nią w kategoriach Levinasowskiego diadycznego modelu modlitwy, który, choćby na poziomie relacji między ...
openaire +2 more sources
The Direct Medial and Lateral Inferior Horizontal Portals of the Knee: A Modified Arthroscopic Approach for Anterior Horn Horizontal Tears. [PDF]
Luo W, Guo D, Liu Z, Liu X.
europepmc +1 more source
Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit +10 more
wiley +1 more source
The internal larval anatomy of two rodent bot fly species: Cuterebra fontinella (Diptera: Oestridae) and Cuterebra americana. [PDF]
Martín-Vega D +3 more
europepmc +1 more source
Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley +1 more source

