Results 41 to 50 of about 121,814 (218)
Oscillatory and nonoscillatory behaviour of solutions of difference equations of the third order [PDF]
Mathematica Bohemica, 2008 Summary: Sufficient conditions are obtained for oscillation of all solutions of third order difference equations of the form \[ y_{n+3} +r_{n} y_{n+2} +q_{n} y_{n+1} +p_{n} y_{n} =0,\quad n\geq 0. \] These results are generalization of the results concerning difference equations with constant coefficients \[ y_{n+3} +ry_{n+2} +qy_{n+1} +py_{n} =0,\quad
Parhi, N., Panda, Anita
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Application of certain Third-order Non-linear Neutral Difference Equations in Robotics Engineering [PDF]
, 2021 S. Sindhuja +4 more
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Oscillation of certain third-order difference equations
Computers & Mathematics with Applications, 2001 New criteria for oscillatory behavior of all solutions of third-order difference equations of the type \[ \Delta^3 x_n=p_n \Delta^2x_{n+m} +q_n F(x_{n-g}, \Delta x_{n-h}) \] are presented.
Agarwal, R.P., Grace, S.R.
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Oscillation of nonlinear third-order difference equations with mixed neutral terms [PDF]
, 2021 Jehad Alzabut +2 more
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On a Third Order Rational Systems of Difference Equations
Annals of the Alexandru Ioan Cuza University - Mathematics, 2014 Abstract In this paper we investigate the form of the solutions of the following systems of difference equations of order three with a nonzero real numbers initial conditions.
N. Touafek, E.M. Elsayed
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FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source