Results 91 to 100 of about 7,387,250 (229)

Life, work and livelihood in the third age: the Carnegie Inquiry into the Third Age: Trinity College Dublin. Friday 31st March, 1995. [PDF]

open access: yes, 1995
The Carnegie Inquiry into the Third Age has added greatly to our understanding of the active years of later life and of the contribution which active older people make to society. We commend the Carnegie Trust for the series of conferences which it is
Carnegie Inquiry in to the Third Age
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Vaginal Fluid hCG Levels for Detecting Premature Rupture of Membranes

open access: yesپزشکی بالینی ابن سینا, 2004
The aim of this study was to determine whether there is any different in hCG levels of vaginal fluids from normal pregnant women, women with confirmed PROM and with suspected PROM.
Tayebeh Artimani
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Does the Angulation of an Impacted Mandibular third Molar Affect the Prevalence of Preoperative Pathoses?

open access: yesJournal of Dentistry, 2019
Statement of the Problem: The removal of a third molar tooth associated with a pathological condition is usually an easy decision. However, it is necessary for clinicians to know about the prevalence of preoperative pathologies associated with impacted ...
Ahmet Altan , Nihat Akbulut
doaj  

Valuing older people, empowering communities, enriching lives

open access: yes, 2013
Third Age is a national voluntary organisation working to promote the value of older people in communities throughout Ireland. Third Age also celebrates the third age as a stage in life when older people are encouraged to remain engaged in family and ...
The Third Age
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Frequency of Facial Skeletal Patterns among Individuals with Impacted Mandibular Third Molars [PDF]

open access: yesمجله دانشگاه علوم پزشکی گرگان
Background and Objective: Impacted mandibular third molars (M3Ms) should be treated promptly after diagnosis. This study aimed to determine the frequency of facial skeletal patterns among individuals with impacted M3Ms.
Aynaz Karimi   +3 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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