Results 111 to 120 of about 5,619,277 (300)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Brain and BehaviorIntroduction Cigarette smoking increases both the risk for insulin resistance and amyloid‐β (Aβ) aggregation, and impaired brain insulin/insulin‐like growth factor 1 (IGF1) signaling might increase risk factors for Alzheimer's disease (AD).
Fan Wang +9 more
doaj +1 more source
On incorporating post-Newtonian effects in N-body dynamics
, 2014 The increasing role of general relativity in the dynamics of stellar systems with central massive black holes and in the evolution of hierarchical triple systems inspires a close examination of how post-Newtonian effects are incorporated into N-body ...
Will, Clifford M.
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Three-body radiation dynamics in systems with anisotropic nanoparticles
, 2015 The time evolution of temperatures of anisotropic nanoparticles in two and three-body systems are simulated for various relative orientations. Nanoparticles are immersed in a thermal bath at constant temperature. It is shown that in two-body systems, the
Nikbakht, Moladad
core +1 more source
Declining body size: a third universal response to warming?
Trends in Ecology & Evolution, 2011 A recently documented correlate of anthropogenic climate change involves reductions in body size, the nature and scale of the pattern leading to suggestions of a third universal response to climate warming. Because body size affects thermoregulation and energetics, changing body size has implications for resilience in the face of climate change.
Gardner, Janet +4 more
openaire +4 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
The theory of long-term behavior of artificial satellite orbits due to third-body perturbations [PDF]
Third-body perturbation effects on satellite orbit reduced to nonlinear system requiring elliptic ...
Lorell, J., Williams, R. R.
core +1 more source
Dimer-atom scattering between two identical fermions and a third particle
, 2010 We use the diagrammatic $T$-matrix approach to analyze the three-body scattering problem between two identical fermions and a third particle (which could be a different species of fermion or a boson).
G. V. Skorniakov +5 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source