Results 81 to 90 of about 5,619,277 (300)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gedanken experiments on nearly extremal black holes and the Third Law
A gedanken experiment in which a black hole is pushed to spin at its maximal rate by tossing into it a test body is considered. After demonstrating that this is kinematically possible for a test body made of reasonable matter, we focus on its ...
Goffredo Chirco +5 more
core +1 more source
The Force Between Two Sliding Bodies When Observed from a Third Moving Body
This paper pertains to the observations of the sliding friction force from different moving bodies. The paper derives the equations required to predict the forces on the free-body diagrams of two sliding bodies when observed from a third moving body. The
Don W. Perumean
doaj +1 more source
Spirituality and health, health and spirituality: a new journey of spirit, mind, and body [PDF]
Epperly, Bruce Gordon. Spirituality and health, health and spirituality: a new journey of spirit, mind, and body.
Meakes, Elizabeth
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Observation of the Efimov state of the helium trimer
Quantum theory dictates that upon weakening the two-body interaction in a three-body system, an infinite number of three-body bound states of a huge spatial extent emerge just before these three-body states become unbound.
Blume, Dörte +11 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Virial expansion with Feynman diagrams
We present a field theoretic method for the calculation of the second and third virial coefficients b2 and b3 of 2-species fermions interacting via a contact interaction. The method is mostly analytic. We find a closed expression for b3 in terms of the 2
A. A. Abrikosov +6 more
core +1 more source

