Results 31 to 40 of about 3,208,800 (253)

Recovery and functional outcome after radial nerve palsy in adults with a humeral shaft fracture: a multicenter prospective case series

open access: yesJSES International, 2023
Background: The consequences of radial nerve palsy associated with a humeral shaft fracture are unclear. The aim of this study was to examine the functional recovery of radial nerve palsy, at presentation or postoperatively, in patients with a humeral ...
Saskia H. Van Bergen, BSc   +42 more
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

Neuro-ophthalmologic symptoms after coronavirus disease 2019 vaccination: a retrospective study

open access: yesBMC Ophthalmology, 2023
Background There have been several studies on inflammatory ophthalmic diseases; however, few studies have reported neuro-ophthalmological symptoms, such as diplopia and ocular motor nerve palsy, after coronavirus disease 2019 (COVID-19) vaccination ...
Kyumin Kang, Se Youp Lee, Dong Cheol Lee
doaj   +1 more source

Trochlear nerve palsy with contralateral Horner's syndrome: A rare presentation post trauma

open access: yesKerala Journal of Ophthalmology, 2021
We describe a case of posttraumatic vertical diplopia and Horner's syndrome (HS). The patient presented 2 weeks post road traffic accident with acute onset double vision more in left gaze and right tilt. The left eye had mild ptosis.
Remya Edachery
doaj   +1 more source

Unilateral Oculomotor Nerve Palsy Secondary to Internal Carotid Artery Aneurysm Without Pupil involvement: A Case Report

open access: yes, 2023
Acquired oculomotor palsies (OMP) can result from numerous factors. The most common causes are presumed microvascular, trauma, compressive neoplasm, postneurosurgery and compression from aneurysm.1,2 ONP caused by internal carotid artery (ICA) aneurysm ...
Danilo Andriatti Paulo; Richard J Blanch
core  

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang   +14 more
wiley   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

Clinical Features and Outcomes of Strabismus Treatment in Third Cranial Nerve Palsy during a 10-Year Period

open access: yesJournal of Ophthalmic & Vision Research, 2014
Purpose: To evaluate the demographics and management outcomes of strabismus surgery in patients with third cranial nerve palsy. Methods: This retrospective study includes subjects with third cranial nerve palsy.
Abbas Bagheri   +3 more
doaj   +1 more source

Third cranial nerve palsy: An unusual presentation of cytarabine toxicity

open access: yesTNOA Journal of Ophthalmic Science and Research, 2023
A 62-year-old male presented with pupil-sparing third cranial nerve palsy. He was not a known case of diabetes mellitus or hypertension. The patient was on cytarabine as a part of treatment for acute lymphoblastic leukaemia (ALL).
Suchismita Mishra   +3 more
doaj   +1 more source

Current Status and Future Perspectives of Robotic Surgery for Esophagogastric Cancer in Asia

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Robotic‐assisted surgery (RAS) has moved from an experimental adjunct to an increasingly established component of gastrointestinal (GI) oncological practice in parts of Asia, a region that carries a disproportionately high burden of gastric and esophageal cancer. Asian surgeons have been among the earliest and most prolific contributors to the
Jia Jun Ang, Jimmy Bok Yan So
wiley   +1 more source

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