Results 81 to 90 of about 2,048,186 (293)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

When “I” or “S/He” uses the product: the impact of narrative perspective on consumers’ brand attitudes in storytelling ads

Frontiers in Psychology
IntroductionStorytelling ad is presented from one or more narrative perspectives. Narrative perspective, which can alter the way in which the plot is physiologically or psychologically perceived, can significantly affect consumer experience.MethodsThis ...
Tingting Chen, Xinqiao Fan, Jiayu He, Jun Fan, Wei Chen   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Augmented reality meeting table: a novel multi-user interface for architectural design [PDF]

, 2004
Immersive virtual environments have received widespread attention as providing possible replacements for the media and systems that designers traditionally use, as well as, more generally, in providing support for collaborative work.
A. A. Argyros, A. Colquhoun, A. Penn, A. Penn, A. Turner, B. Hillier, B. Hillier, B. Hillier, B. Hillier, B. Hillier, B. Lawson, B. Wanstall, C. Jones, C. Jones, D.A. Schoen, D.A. Schoen, G. Stiny, H. Rittel, H. Simon, H. Simon, H.T. Regenbrecht, J.F.H. Fuchs, L. Archer, N. Navab, N.J. Habraken, P. Checkland, P. Checkland, R. Venturi, R.T. Azuma, R.T. Azuma, S. Feiner, S. Weghorst   +31 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Author’s “Ego” in “The Ballad of the Reading Gaol”

Armenian Folia Anglistika, 2014
Oscar Wilde’s poem “The Ballad of the Reading Gaol” contains various narrative perspectives which convey the author’s and the protagonist’s points of view.
Marika Tonyan
doaj   +1 more source

Eye of the Beholder: Memory Recall Perspective Impacts Nostalgia’s Influence on Positive Affect

Frontiers in Psychology, 2020
Recalling memories for which one is nostalgic provides a host of psychological benefits, including promoting positive affect. The present research (N = 409) examined how memory recall perspective impacts this affective consequence of waxing nostalgic ...
Ross Rogers
doaj   +1 more source

Seeing pain and pleasure on self and others: behavioural and psychophysiological reactivity in immersive virtual reality [PDF]

, 2016
Studies have explored behavioral and neural responses to the observation of pain in others. However, much less is known about how taking a physical perspective influences reactivity to the observation of others' pain and pleasure.
AGLIOTI, Salvatore Maria, FUSARO, MARTINA, TIERI, GAETANO   +2 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source