Results 91 to 100 of about 12,394,740 (332)

Third Space of Legal Translation: Between Protean Meanings, Legal Cultures and Communication Stratification

International Journal for the Semiotics of Law, 2020
Legal translation is a complex transfer of the text formulated in a source language into a target language which needs to take into account a wide array of factors to ensure the equality of parties to the process of interlingual communication.
Aleksandra E. Matulewska, A. Wagner
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Bridging the gap: a new approach to student academic support at the University of Exeter

Journal of Learning Development in Higher Education
A review carried out during the spring of 2023 identified a need for a new approach to student academic support at the University of Exeter. The model places pastoral mentors within departments to bridge the ‘third space’ gap between academic and ...
Nicky King, Jess Johnson, Hannah Jordan, Hannah Lyons   +3 more
doaj   +1 more source

Geographical Proximity is not Enough: How Culture Shaped Placement, Spatiality, and the Outcomes of the Arab Spring's Uprising

Glocalism: Journal of Culture, Politics and Innovation, 2017
This paper investigates the phenomenon of the Arab Spring against the background of cultural traditions and attitudes that sustained these protests and carried them across borders of more than twenty countries in the Middle East in a move of cultural ...
Olesya Venger
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Education-focused academics in pursuit of third-space visibility: a five-step process

Journal of Learning Development in Higher Education
Education-focused academics were introduced to enhance the quality of education and assist universities in addressing sector metrics that would place them favourably within an increasingly competitive environment.
Antonios Kaniadakis, Fiona Denney
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Pedagogical content knowledge as a model for academic development practice in the third space

Journal of Learning Development in Higher Education
In this opinion piece, I make the case for the use of Shulman’s concept of Pedagogical Content Knowledge as both a practical and philosophical approach to academic development work in the third space.
Erik Brogt
doaj   +1 more source

In-between access and transformation: analysing a university writing centre’s academic support programme for education students as third space

Stellenbosch Papers in Linguistics Plus, 2019
This paper reports on ongoing research into how an embedded academic support programme, based in a South African university’s writing centre, shapes the academic literacy practices of first-year B.Ed. students. This paper focuses specifically on the peer
Namakula, Halima, Maria Prozesky
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source