Results 61 to 70 of about 12,394,740 (332)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Innovation and entrepreneurship in organizational university “Third Space” arrangements: Third Space and third mission in mode 3 universities

Journal of Innovation and Entrepreneurship
This article explores how Third Space Professionals in Mode 3 universities help bridge academic research and real-world application, fostering innovation, entrepreneurship, and social progress.
Barbara Pöcher, David F. J. Campbell, Elias G. Carayannis   +2 more
doaj   +1 more source

“An Odyssey of Third Space Endoscopy”—from Entry into the Tunnel to Entry into the Peritoneal Cavity

Journal of Digestive Endoscopy, 2019
The last decade has seen the growth of a completely new and exciting entity called the third space endoscopy (TSE) that has brought about a paradigm shift in the way we manage various disorders of the gastrointestinal tract.
Harshal S. Mandavdhare, Shubhra Mishra, Jayanta Samanta, Jimil Shah, Rakesh Kochhar   +4 more
doaj   +1 more source

Blended professionals, technology and online learning: Identifying a socio‐technical third space in higher education

Higher Education Quarterly, 2020
The idea of a ‘third space’ located between academic and professional domains has proven useful in exploring changing academic and professional roles in higher education, including in online learning.
S. White, Su White, Kate Borthwick
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Third-order chromatic dispersion stabilizes Kerr frequency combs

, 2014
Using numerical simulations of an extended Lugiato-Lefever equation, we analyze the stability and nonlinear dynamics of Kerr frequency combs generated in microresonators and fiber resonators taking into account third-order dispersion effects.
Coen, Stephane, Gelens, Lendert, Gomila, Damia, Leo, Francois, Parra-Rivas, Pedro   +4 more
core   +1 more source

Quasi-symmetric invariant properties of Cantor metric spaces [PDF]

, 2019
For metric spaces, the doubling property, the uniform disconnectedness, and the uniform perfectness are known as quasi-symmetric invariant properties. The David-Semmes uniformization theorem states that if a compact metric space satisfies all the three ...
Ishiki, Yoshito
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A learner developer perspective: critiquing dominant practices and cultures within university spaces

Journal of Learning Development in Higher Education, 2018
This commentary reflects my evolving understanding of the problematic nature of identity and how this relates to notions of professional identity for those in learning development (LD) roles who engage with and produce research. If identity is, as Quinn (
Sarah Parkes
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source