Results 51 to 60 of about 10,425,062 (302)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

TWSC at Forty: Multidisciplinary Research and the Challenges to the Center [PDF]

open access: yes, 2018
Notes from the editor on this special issue on the commemoration of the fortieth anniversary of the University of the Philippines Third World Studies ...
Philippine Journal of Third World Studies, Kasarinlan
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Political Cataclysms at the Start of the Century and the Future of the International Relations System

open access: yesVestnik MGIMO-Universiteta, 2015
: Crises in Ukraine and the Middle East indicate the existence of deep shifts in the global international relations system. These shifts are much more serious than the widely discussed erosion of the US international monopoly and are related to the ...
A. V. Korobkov
doaj   +1 more source

The Managing of the (Third) World [PDF]

open access: yesOrganization, 2004
Abstract This article is about the relationship between management and the Third World. Its significance, however, is for understandings of management in and of both First and Third Worlds. It builds from an agreement with Diana Wong- MingJi and Ali Mir (1997) that what is taken as ‘management’ in the First World, in the field of ...
openaire   +2 more sources

World Development Indicators 2010

open access: yes, 2010
The 1998 edition of world development indicators initiated a series of annual reports on progress toward the International development goals. In the foreword then, World Bank President James D. Wolfensohn recognized
World Bank
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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