Results 61 to 70 of about 10,425,062 (302)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The United States and the Events of 1965–1966 in Indonesia
In 1965–1966 Indonesia experienced mass killings of communists and Leftists, as well as ethnic Chinese, who were thought to be members of pro-communist organizations.
E. N. Glazunova, A. S. Manykin
doaj
The Manipulation of Indonesia's Ethnic Chinese: The TWSC Interview with Ariel Heryanto [PDF]
The fall of Suharto has been viewed as the Southeast Asian region's most astonishing event of late. The tension and destruction in Jakarta and other Indonesian cities and the former dictator's startling ouster sent the country of 200 million into a wave ...
Center, Third World Studies
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The 2015 Third World Studies Center Writeshop [PDF]
Introduces the content of Kasarinlan: Philippine Journal of Third World Studies, volume 30, number 1 (2015), "The 2015 Third World Studies Center Writeshop.
Jose, Ricardo T.
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Vaccines for the Third World [PDF]
New vaccines, developed through genetic engineering, can make immunization an even more effective weapon for tackling disease in developing countries. So what is preventing progress?
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

